Black people and women are worst-off – blacks because they mainly work in the informal sector and women because they are mainly considered non-essential workers.
In an article published in the Journal of Pineal Research, researchers at São Paulo State University and collaborators describe a set of genes potentially regulated by the “sleep hormone” in some types of tumor
In vitro studies and experiments with mice show that the natural extract was more effective than the only drug available to combat this parasitic disease.
Experiments with mice and humans showed that exercise training increased the expression in adipose tissue of a key enzyme for the organism’s metabolic health, combating the harmful effects of aging and obesity.
Medication originally developed to kill bacteria displayed the capacity to increase cell energy expenditure in tests with mice. Researchers at the University of Campinas and the biopharmaceutical AstraZeneca are testing compounds with a similar structure that could give rise to novel approaches to the treatment of obesity.
In defense cells from patients hospitalized with the disease, Brazilian researchers found signs of activation of a protein complex called the inflammasome, responsible for initiating the inflammatory response that can damage organs and lead to death. The findings could help identify drugs capable of interrupting the process.
An article in Cell by researchers affiliated with Harvard and the University of São Paulo shows that the metabolite succinate is released by muscle cells during physical exercise and triggers a process of tissue remodeling that makes muscles stronger and enhances metabolic efficiency.
Roadmap proposes 25 research priorities in strategic areas to build a more equitable, resilient and sustainable future.
Food engineers in Brazil and France developed gels based on modified starch for use as “ink” to make foods and novel materials by additive manufacturing.
The special series “Field Diary” (“Diário de Campo”) features University of São Paulo scientists Marcelo Urbano Ferreira and Marly Augusto Cardoso on an expedition to Mâncio Lima, a small town in the Amazon where they collect samples from patients to investigate transmission of the novel coronavirus.
Study by Brazilian researchers reported in Nature Communications shows that trees are growing faster in forests worldwide, including the Amazon, but their lives are getting shorter.
Genetic mapping of the shark’s liver and eye tissue showed overexpression of nine genes known for action in tumor suppression, wound healing, and probable monochrome vision. The species is considered globally endangered and caught on a large scale by industrial fishing vessels.
With FAPESP’s support, the Nuclear and Energy Research Institute is assembling a world-class laboratory that associates nanotechnology with radiopharmacy. The aim is to develop new products, mainly for cancer treatment.
Study by FAPESP-Shell Engineering Research Center hosted at University of Campinas set out to develop supercapacitors that store more energy and batteries that charge faster.
Researchers at the University of São Paulo identified proteins found at augmented levels in the blood plasma of high-risk patients using equipment present in Brazilian hospitals. The result of the test could help physicians make better-targeted decisions.
Study shows that a tree frog endemic to a mountainous region of the Brazilian savanna is unable to disperse and find genetically closer mates when the terrain is rugged, potentially endangering survival of the species. The findings show that topography is an important factor for conservation policy.
An article in Science Advances shows high school students are steadily becoming more sensitive to environmental and scientific ideas. However, interest is uneven in regional terms. It is most intense in the North, less so in the Southeast.
Analysis of DNA from 1,171 over-sixties living in São Paulo will enable scientists to identify genetic mutations responsible for diseases or important to healthy aging, according to the authors of the study.
In laboratory tests, the material eliminated 79.9% of SARS-CoV-2 particles in three minutes and 99.99% in up to 15 minutes.
Preliminary results of patient tissue analysis show that the virus infects adipocytes and alters the quantity of signaling molecules released by these cells into the bloodstream.
Scientists at a research center supported by FAPESP identified a non-inherited mutation in blood cells from a patient with GATA2 deficiency that may have prevented bone marrow failure and other clinical manifestations.
A cross-border team of researchers refute arguments that carbon debt, opportunity cost and indirect land-use change prevent greenhouse gas mitigation by biofuels.
Research shows how Nef subverts human cells’ defense mechanisms to enable HIV to advance; Brazilian scientists comment on progress in this area in Nature group journal article.
Monoclonal antibody tested by researchers at University of São Paulo and experimental drug given to patients in Italy by University of Pennsylvania research group promoted rapid improvement of respiratory function in patients hospitalized in severe condition.
Incentives to drive a rapid recovery by the sector, one of the hardest hit by the COVID-19 pandemic, will contribute to a resumption of world economic growth, save or create millions of jobs, and contain global emissions of carbon dioxide, experts say.
