By combining acoustic levitation and X-ray diffraction with synchrotron light, the researchers were able to analyze the interactions of a drug’s atoms in real time and improve its formulation.
The finding by Brazilian researchers was based on data for 3,587 adolescents who took part in the US National Health and Nutrition Examination Survey (NHANES). Another finding of concern is a 63% higher risk of visceral obesity, which correlates closely with metabolic and cardiovascular diseases.
Results published in Scientific Reports by a research group at the Federal University of São Paulo help scientists understand why patients with metabolic syndrome are among those worst affected by COVID-19.
These ants emerged some 8.5 million years ago and underwent an intense speciation process between 1 million and 3 million years ago, when the Brazilian savanna was expanding. The recent advance of agriculture in the region, however, appears to be reducing this biodiversity and selecting species that damage crops.
Known as pineapple sett rot, the disease reduces cane budding by up to 50%. Results obtained by scientists in Brazil will bolster the search for biological fungicides that offer an alternative to agrochemicals.
The importance of innovation was stressed by participants in the ninth FAPESP 60 Years Conference, who also highlighted the fall in public-sector investment in R&D in recent years.
This was the main finding of a study by scientists affiliated with a FAPESP-supported research center. The effect may be associated with a mechanism whereby the fruit increases expression of an insulin-related microRNA.
In an editorial in the British Journal of Sports Medicine, Bruno Gualano, a professor at the University of São Paulo (Brazil), reviews what scientists know about the relationship between regular exercise and the disease caused by SARS-CoV-2.
The point was stressed by Jean Ometto, a senior researcher at Brazil’s National Space Research Institute (INPE) and a Lead Author of the latest installment of the IPCC’s Sixth Assessment Report, during a webinar held by FAPESP. Four other Brazilian researchers who contributed to the document also took part in the event.
Researchers at the University of São Paulo have developed a portable device made from graphite, silver particles and polyurethane that detects BPA, a chemical compound harmful to health and considered an indicator of the presence of emerging pollutants in river or tap water.
Brazilian researchers analyzed the mechanisms by which estuarine plants absorb iron at the mouth of the Doce River, which was polluted by massive amounts of tailings from the 2015 Fundão dam disaster.
A study shows how extracellular vesicles share information among cells in the same species, enabling the colony to respond in a coordinated manner to the host organism’s defenses.
Pythiosis affects humans, horses and other animals, often requiring surgery and even amputation. A study conducted at São Paulo State University has discovered seven potential antigens that can serve as a basis for tests and vaccines.
A study by researchers at the University of São Paulo advocates closer monitoring of these patients and prescribing more powerful drugs to combat atherosclerosis.
Scientists at a FAPESP-funded research center reprogrammed skin cells from patients with epilepsy to differentiate into cortical organoids with hallmarks of the malformation known as focal cortical dysplasia.
Species sensitive to habitat change are gradually being replaced by more resistant species, according to a study conducted in Brazil. The trend is leading to a loss of the ecological functions performed by the vanishing species.
Whole-genome sequences of 1,171 elderly people living in São Paulo City were analyzed to detect mutations responsible for disease or that play a key role in healthy aging.
Brazilian researchers measured this increase in immunity in a study involving health workers who had received two doses of CoronaVac. In subjects given the Oxford-AstraZeneca vaccine, the same booster raised immunity by a factor of 7.
Triple-negative breast cancer grows rapidly and is highly likely to metastasize. Experiments with mice identified a molecule that binds to a defense cell receptor and activates an immune response against the tumor.
The app is one of the outcomes of an initiative by researchers in Brazil, Germany and the UK to engage local communities in generating data on flood-prone areas. The researchers are also collecting memories of past incidents.
Genetic sequencing enables scientists to identify 79 different species of coralline algae serving as a habitat for countless marine organisms on the Brazilian coast, with many yet to be explored in deep waters.
The strategy was tested at the Federal University of São Carlos and found to permit a reduction in the amount of fertilizer used by farmers, mitigating its environmental impact.
Researchers at São Paulo State University followed young men and women aged 20-40 without pre-existing disease. The findings show that obesity and physical inactivity increase the impact of the disease on the autonomic nervous system, which regulates blood pressure, heart rate and breathing, among other functions.
First-ever study to show correlation between inhibition of protein HSP70 and dysfunction of cells in inner lining of blood vessels, one of the factors involved in chronic thromboembolic pulmonary hypertension.
Brazilian scientists tested a participatory disaster risk monitoring strategy in a town that was partially destroyed in 2010 after an unprecedented flood. The methodology can be applied in other parts of the country.
