In experiments involving rats, researchers at São Paulo State University found that periods of low oxygen levels in the first months of life can lead to dysregulation of the sympathetic autonomic nervous system, which controls functions such as heart rate and blood pressure. The discovery points to possible routes to the development of novel therapies.
A biodressing containing human umbilical cord stem cells was produced in a 3D printer by the startup In Situ Cell Therapy. Researchers at the University of São Paulo found that when used on diabetic mice, the “smart” biodressing modulated the immune response, stimulated collagen synthesis and enhanced tissue repair.
FAPESP has funded more than 40,000 research projects linked to one or more SDGs, said Marco Antonio Zago.
Leishmania alters the structure of the human protein that would normally induce the death of infected cells and weakens the inflammatory response. Reported in Nature Communications, the discovery could serve as a basis for better treatment.
An analysis conducted at the University of São Paulo showed that no sample exceeded the recommended limit for aflatoxin M1, a contaminant of fungal origin considered carcinogenic. Nevertheless, the researchers warn of the need to demand best practices in dairy production.
No fewer than eight important hydrographic basins depend on the ecosystems that make up the Cerrado, Brazil’s savanna-like biome, but ambiguities in the legislation have permitted the advance of soybean plantations in the region. The warning is in an article by Brazilian researchers in the journal Perspectives in Ecology and Conservation.
A study by researchers at the State University of Campinas showed that although the two types of training produce similar metabolic stress, muscle activation is different.
Ricardo Galvão, President of the National Council for Scientific and Technological Development (CNPq), discussed the status quo and outlook for Brazilian science in the first of the 2023 FAPESP Lectures.
Brazilian researchers observed an increase in production of endocannabinoid, a natural anti-inflammatory neurotransmitter, in COVID-19 patients given glucocorticoids. The discovery points to possibilities of novel treatments for various inflammatory and neurological diseases.
Scientists at São Paulo State University repurposed a device already used to analyze bovine reproductive cells to observe different characteristics of human sperm simultaneously.
A sprayable solution developed by researchers at the State University of Campinas does not spread rapidly over a surface and efficiently eliminates harmful microorganisms. The technology can be licensed from the university’s innovation agency.
In vitro experiments were conducted at a FAPESP-supported research center with a synthetic peptide inspired by molecules secreted by the probiotic bacterium Lactobacillus plantarum.
A program developed by researchers at the University of São Paulo included three weekly sessions of up to 80 minutes each for 16 weeks, with positive effects on cardiorespiratory fitness, lung function, functional capacity, body composition and persistent symptoms.
An online event presented the results of five projects selected in a call issued by FAPESP in partnership with the Belmont Forum and JPI Urban Europe.
Predictive model developed at São Paulo State University (UNESP) helps identify tumor biomarkers of this metabolic syndrome characterized by acute weight loss and muscle wasting.
In laboratory mice, the hormone easily bought from pharmacies and widely consumed as a supplement aggravated Crohn’s disease and ulcerative colitis, depending on the animal’s gut microbiota profile, according to a study by researchers at the University of São Paulo.
In an interview given to Agência FAPESP, the new director reveals his plans to seek more partnerships with institutions, strengthen the Foundation’s international ties and simplify processes by cutting bureaucracy.
Representatives of 44 startups will receive 12 months of technical support for the development of products and processes through in-person training, mentoring and workshops run by experts from FAPESP and institutions that promote innovative entrepreneurship.
Researchers show the importance of political skill on the part of federal research institution Fiocruz and regulatory agency ANVISA in the process that resulted in the signature of an agreement with pharmaceutical company AstraZeneca in mid-pandemic.
The most comprehensive sequencing to date of the genomes of the Leatherback and Green sea turtles shows they are mostly identical. An article in PNAS helps scientists understand how the group has evolved and provides ideas for conservation strategies.
In a study with 116 participants, researchers at the Federal University of São Paulo evaluated the genetic material contained in extracellular vesicles possibly secreted by brain tissue. The analysis pointed to patterns of microRNA expression associated with depression, anxiety and ADHD.
A startup based in São Paulo is working with research centers, laboratories and private enterprise to develop novel medications from plant-based natural products. The drugs will be designed to combat multifactorial diseases.
Representatives of German universities, research institutions and funding agencies were welcomed at FAPESP’s headquarters in late March. The Amazon and renewable energy are areas of interest for new bilateral partnerships.
A webinar co-hosted by the two organizations featured researchers from São Paulo and the southeast African country discussing ways to promote scientific collaboration in areas such as climate change, natural disaster monitoring, agriculture, health, and bioenergy.
Tested by Brazilian and British researchers, the process is an example of circular economy technology, in which waste produced in one economic activity is converted into resources for other sectors.
