Detected in the state of Ceará, Brazil, the novel coronavirus has similarities with the coronavirus that causes Middle East respiratory syndrome, first identified in 2012. Experiments to find out whether it can infect humans are set to take place during 2025.
Already provided by the UK’s National Health Service, the approach, called PACT, aims to improve communication and interaction by focusing on the child’s interests.
Fish oil supplementation altered the profile of defense cells, which switched from a pro-inflammatory to an anti-inflammatory state, reversing a condition similar to type 2 diabetes.
The method developed at the University of São Paulo detects and distinguishes between antibodies induced by the pathogens in blood samples. The strategy can be used to orient public policy in health and to evaluate the efficacy of dengue vaccines.
Researchers used an innovative approach and analyzed data from a large sample involving residents of four state capitals in different regions of Brazil; study contributes to preventive strategies for this type of tumor.
A study conducted at the University of São Paulo analyzed the effectiveness of 12 models and showed that only one met the safety limits set by an international organization.
The conclusion comes from a study that analyzed data from more than 3,600 adolescents aged 14 to 17. Moderate screen time spent on educational activities was associated with less psychological distress.
The world’s largest study of the impact of dietary polyphenol intake on the risk of cardiometabolic problems tracked more than 6,000 Brazilians for eight years.
A study involving 173 pregnant women reached this conclusion. The findings expand scientific knowledge of the preeclampsia and the mechanisms whereby damage to the kidneys, lungs, liver and brain may occur.
A study of 153 people between the ages of 60 and 89 suggests modifications to a well-established clinical test for assessing balance in the elderly to make it more efficient, accessible, and predictive.
By creating a new metric, researchers envision the possibility of diagnostic and treatment advances for the disease, which is estimated to affect about 4 million people worldwide.
The population is not immunized against DENV-3. Meanwhile, DENV-1 and -2 continue to circulate, experts warn.
Researchers at a FAPESP-supported research center have identified the key role of the GenB2 enzyme in the formation of gentamicin components. The findings make it possible to develop safer and more selective versions of the drug.
The phase 3 clinical trial showed that Butantan-DV is effective against dengue virus types 1 and 2, which were circulating at the time. The results can be extrapolated for types 3 and 4 based on additional in vitro testing, according to the researchers.
Using a single-cell sequencing technique, it was possible to characterize the different cell types present in the brain lesion. The result paves the way for specific treatments against focal cortical dysplasia.
Scientists at the University of São Paulo analyzed blood samples donated by six serodiscordant couples where female partners were resistant to SARS-CoV-2 despite intense contact with their infected male partners. Overexpression of the gene IFIT3 in these asymptomatic women suggests it affords protection and could be a target for novel antiviral therapies.
Studies conducted at the State University of Campinas have shown that physical training, combining strength training and aerobic exercise, improves lipid metabolism, reduces inflammation and reverses early immunosenescence in obese and diabetic individuals.
Study involved 242 couples living in the Metropolitan Region of São Paulo (Brazil); men showed higher levels of work-family conflict, while women were more affected by stress.
Researchers isolated a strain of Pseudomonas alcaligenes that can withstand temperatures as high as 44 °C from a hot spring in Chile, and characterized the substances produced by the bacterium that help it survive extreme conditions.
The ‘Best Oral Presentation’ award at an event promoted by the Hospital de Amor in Barretos (São Paulo state) was given to doctoral student Mariane Tirapelle, who is part of the Cell Therapy Center and the Nucleus of Cellular Therapy teams.
System developed by FAPESP-supported startup provides information and guidance after hospital discharge.
The vaccine formulation has proved to be highly protective, safe and versatile. Moreover, it can serve as a basis for the development of zika and dengue vaccines, for example.
USP is developing the vaccine in partnership with the Vaccine Technology Center at the Federal University of Minas Gerais (UFMG). Permission to conduct a clinical trial is due before the end of this month.
The researchers synthesized a molecule inspired by a substance present in Nectandra leucantha (canela-seca or canela-branca). Animal trials have produced promising results.
Researchers tested the effects of the plant’s methanolic extract and an isolated alkaloid substance, palmatine, on mice. The results were promising.
