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FAPESP and the Sustainable Development Goals

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SDG 3 Good Health and Well-being

News

SDG 3 Good Health and Well-being

Older men who sleep more than nine hours are at greater risk of losing mobility
SDG 3
Older men who sleep more than nine hours are at greater risk of losing mobility

A study followed more than 3,000 people over the age of 60 for eight years and found that this decline is not observed in women.


Sickle cell anemia: Treatment for the disease that ushered in molecular medicine faces barriers of inequality and racism
SDG 3
Sickle cell anemia: Treatment for the disease that ushered in molecular medicine faces barriers of inequality and racism

Research on sickle cell anemia spurred the development of genetic technologies, but there is an urgent need to democratize access to modern therapies, noted French hematologist Jacques Elion at a conference hosted by FAPESP.


Technology uses quantum properties to accelerate the search for new drugs
SDG 3, SDG 9
Technology uses quantum properties to accelerate the search for new drugs

Startup develops a sensor that measures interactions between molecules with high precision, which can reduce the time and costs of discovering drug candidates.


Study explains how the Chagas disease parasite ‘activates’ its form capable of infecting mammals
SDG 3
Study explains how the Chagas disease parasite ‘activates’ its form capable of infecting mammals

Understanding how Trypanosoma cruzi manipulates its own RNA to alter protein production and invade the host could lead to new therapeutic approaches against the disease.


Study explains how the Chagas disease parasite ‘activates’ its form capable of infecting mammals
SDG 3
Study explains how the Chagas disease parasite ‘activates’ its form capable of infecting mammals

Understanding how Trypanosoma cruzi manipulates its own RNA to alter protein production and invade the host could lead to new therapeutic approaches against the disease.


Air pollution induces changes in the oral mucosa and worsens periodontal disease
SDG 3
Air pollution induces changes in the oral mucosa and worsens periodontal disease

Research conducted on mice provides experimental evidence that exposure to PM2.5, a main component of urban air pollution, increases oxidative stress, intensifies inflammatory responses, and worsens the destruction of periodontal tissues.


Air pollution induces changes in the oral mucosa and worsens periodontal disease
SDG 3
Air pollution induces changes in the oral mucosa and worsens periodontal disease

Research conducted on mice provides experimental evidence that exposure to PM2.5, a main component of urban air pollution, increases oxidative stress, intensifies inflammatory responses, and worsens the destruction of periodontal tissues.


Nanoparticle combines two strategies to speed up the healing of chronic wounds
SDG 3
Nanoparticle combines two strategies to speed up the healing of chronic wounds

A topical formulation brings together natural antioxidant and the genetic silencing of an enzyme that degrades cutaneous tissue. In laboratory tests, the treatment promoted full cell regeneration in just 72 hours.


Nanoparticle combines two strategies to speed up the healing of chronic wounds
SDG 3
Nanoparticle combines two strategies to speed up the healing of chronic wounds

A topical formulation brings together natural antioxidant and the genetic silencing of an enzyme that degrades cutaneous tissue. In laboratory tests, the treatment promoted full cell regeneration in just 72 hours.


New technique reveals on a large scale how thousands of proteins change shape and move
SDG 3, SDG 9
New technique reveals on a large scale how thousands of proteins change shape and move

Led by a Brazilian researcher, a study published in Nature shows that molecules with nearly identical three-dimensional structures can exhibit completely different behaviors over time.


Study seeks innovative therapies against COVID-19
SDG 3
Study seeks innovative therapies against COVID-19

A researcher affiliated with a FAPESP-funded center is studying monoclonal antibodies capable of neutralizing different variants of SARS-CoV-2.


Use of omega-3 and ASA has a similar effect to antibiotics against severe periodontitis
SDG 3
Use of omega-3 and ASA has a similar effect to antibiotics against severe periodontitis

Study shows that combining the two compounds with conventional treatment may be a promising alternative, reducing the need for antibiotics.


Mega-study analyzes the impact of gratitude interventions
SDG 3
Mega-study analyzes the impact of gratitude interventions

Research conducted in 34 countries compared six practices designed to foster gratitude with three control measures, observing variations in effects based on cultural differences.


Genetic testing changes the course of hereditary cancer in a family observed for 20 years
SDG 3
Genetic testing changes the course of hereditary cancer in a family observed for 20 years

A case report published in the journal CA: A Cancer Journal for Clinicians shows how genetic analysis and molecular biology studies helped confirm the diagnosis, guide preventive surgeries, and define personalized surveillance strategies across generations.


New vaccine strategy protects against chikungunya and could become a platform for combating other diseases
SDG 3
New vaccine strategy protects against chikungunya and could become a platform for combating other diseases

In tests conducted on mice, a single dose of the formulation containing genetically modified viruses protected the rodents against the disease.


Study points to a link between hypothyroidism and sleep apnea
SDG 3
Study points to a link between hypothyroidism and sleep apnea

Research involving residents of São Paulo (Brazil) suggests a bidirectional relationship between the two conditions and indicates the benefits of hormone therapy for improving sleep quality.


Genetic map produced in Brazil points to new avenues for treating Alzheimer’s
SDG 3, SDG 9
Genetic map produced in Brazil points to new avenues for treating Alzheimer’s

A São Paulo-based startup has identified 129 new research targets that could lead to new methods for diagnosing and treating the disease.


Combination of abdominal obesity and vitamin D deficiency more than doubles the risk of death in people over 50
SDG 3
Combination of abdominal obesity and vitamin D deficiency more than doubles the risk of death in people over 50

A study involving over 5,500 individuals indicates that hormone level monitoring and weight control are essential measures to avoid premature death.


A high-sugar diet may worsen asthma, even in the short term
SDG 3
A high-sugar diet may worsen asthma, even in the short term

In a study conducted on mice, high consumption of condensed milk induced a fast inflammatory response in abdominal adipose cells that extended to the lungs.


RIDC CancerThera signs partnership with Uruguayan institution to accelerate new frontier in cancer therapy
SDG 3
RIDC CancerThera signs partnership with Uruguayan institution to accelerate new frontier in cancer therapy

The agreement between the FAPESP Research, Innovation, and Dissemination Center and the Uruguayan Center for Molecular Imaging aims to boost the development and application of theranostic radiopharmaceuticals.


Study shows that social inequality exacerbates barriers to physical activity
SDG 3
Study shows that social inequality exacerbates barriers to physical activity

Black, mixed-race, Asian, and Indigenous women with lower levels of education face greater difficulties. The study followed the same group for a decade.


The consumption of ultra-processed foods by fathers may influence their babies’ birth weight and body measurements
SDG 3
The consumption of ultra-processed foods by fathers may influence their babies’ birth weight and body measurements

A study conducted at the University of São Paulo reinforces the importance of including fathers in health and family planning guidance.


Study identifies measures that aid in the recovery of patients with fractures near the shoulder
SDG 3
Study identifies measures that aid in the recovery of patients with fractures near the shoulder

The analysis identified the line between normal care regarding movement for those who have suffered an injury and excessive fear, which ultimately hinders rehabilitation.


Weight training reprograms liver cells and helps reverse obesity-related damage
SDG 3
Weight training reprograms liver cells and helps reverse obesity-related damage

A study by the State University of Campinas using mice reveals that strength training modulates the liver’s genome, restoring insulin sensitivity and combating fat accumulation in the organ.


New research center will use smartwatches and smart rings for early disease detection
SDG 3
New research center will use smartwatches and smart rings for early disease detection

Created by FAPESP, the State University of Campinas, and Samsung, Viva Bem will develop algorithms and AI technologies embedded in these devices to detect signs of Parkinson’s disease and other conditions even before symptoms appear.


News about research projects funded by FAPESP and articulated with the SDGs: