Fapesp

FAPESP and the Sustainable Development Goals

News

SDG 3 Good Health and Well-being

News

SDG 3 Good Health and Well-being

Study proposes safer alternative for hormone replacement therapy during menopause
SDG 3
Study proposes safer alternative for hormone replacement therapy during menopause

Experiment with female rats shows that treatment targeting only one estrogen receptor provides metabolic protection without the risk of stimulating tumors in the uterus and breasts.


Starch-based sensor changes color to indicate moisture in food packaging
SDG 3
Starch-based sensor changes color to indicate moisture in food packaging

Developed at the University of São Paulo, the smart device uses cobalt chloride to detect a loss of crispness in products such as cookies.


‘Supergraft’ reconstructs bone and fights infections simultaneously
SDG 3, SDG 9
‘Supergraft’ reconstructs bone and fights infections simultaneously

Startup develops technology that accelerates bone regeneration and reduces the risk of complications after surgery.


Strength training causes fat cells to shrink even before weight loss
SDG 3
Strength training causes fat cells to shrink even before weight loss

A study with mice conducted at the State University of Campinas shows that seven days of strength training were sufficient to activate lipid breakdown mechanisms.


Brazilian researcher participates in project to expand diversity of African genomes in public databases
SDG 3, SDG 10
Brazilian researcher participates in project to expand diversity of African genomes in public databases

In partnership with Angolan researchers, a professor from the State University of Campinas will lead the sequencing of 750 DNA samples from Angola. The data will contribute to the development of precision medicine.


Device simulates human tissue and offers an alternative to animal testing
SDG 3, SDG 9
Device simulates human tissue and offers an alternative to animal testing

Developed at the Brazilian Center for Research in Energy and Materials, this technology enables the three-dimensional cultivation of cells and allows for a more accurate assessment of the toxicity of drugs, nanomaterials, and pollutants.


Cigarette butts are the most common type of litter on the planet, with 4.5 trillion being discarded each year
SDG 3, SDG 6, SDG 12, SDG 14
Cigarette butts are the most common type of litter on the planet, with 4.5 trillion being discarded each year

A review study compiling scientific data from 55 countries reveals alarming levels of pollution in urban and aquatic environments. Not even protected and remote areas are completely free from the problem.


Supporting children with mental disorders accounts for 50% of a family’s monthly income
SDG 3
Supporting children with mental disorders accounts for 50% of a family’s monthly income

The data are from a project linked to the Center for Research and Innovation in Mental Health, one of the Applied Research Centers funded by FAPESP. The study was conducted with 1,158 caregivers of young people aged 14 to 23.


Increasing daily steps is as effective as aerobic exercise in managing asthma
SDG 3
Increasing daily steps is as effective as aerobic exercise in managing asthma

A clinical trial conducted at the University of São Paulo demonstrated that both non-pharmacological approaches improve quality of life and alleviate respiratory and anxiety symptoms in the medium term.


Researchers turn broken bean grains into a high-value protein ingredient
SDG 3, SDG 9, SDG 12
Researchers turn broken bean grains into a high-value protein ingredient

Developed at the Institute of Food Technology with support from FAPESP, the innovation could serve as an alternative to proteins from soybeans or peas, which are largely imported.


Older men who sleep more than nine hours are at greater risk of losing mobility
SDG 3
Older men who sleep more than nine hours are at greater risk of losing mobility

A study followed more than 3,000 people over the age of 60 for eight years and found that this decline is not observed in women.


Sickle cell anemia: Treatment for the disease that ushered in molecular medicine faces barriers of inequality and racism
SDG 3
Sickle cell anemia: Treatment for the disease that ushered in molecular medicine faces barriers of inequality and racism

Research on sickle cell anemia spurred the development of genetic technologies, but there is an urgent need to democratize access to modern therapies, noted French hematologist Jacques Elion at a conference hosted by FAPESP.


Technology uses quantum properties to accelerate the search for new drugs
SDG 3, SDG 9
Technology uses quantum properties to accelerate the search for new drugs

Startup develops a sensor that measures interactions between molecules with high precision, which can reduce the time and costs of discovering drug candidates.


Study explains how the Chagas disease parasite ‘activates’ its form capable of infecting mammals
SDG 3
Study explains how the Chagas disease parasite ‘activates’ its form capable of infecting mammals

Understanding how Trypanosoma cruzi manipulates its own RNA to alter protein production and invade the host could lead to new therapeutic approaches against the disease.


Study explains how the Chagas disease parasite ‘activates’ its form capable of infecting mammals
SDG 3
Study explains how the Chagas disease parasite ‘activates’ its form capable of infecting mammals

Understanding how Trypanosoma cruzi manipulates its own RNA to alter protein production and invade the host could lead to new therapeutic approaches against the disease.


Air pollution induces changes in the oral mucosa and worsens periodontal disease
SDG 3
Air pollution induces changes in the oral mucosa and worsens periodontal disease

Research conducted on mice provides experimental evidence that exposure to PM2.5, a main component of urban air pollution, increases oxidative stress, intensifies inflammatory responses, and worsens the destruction of periodontal tissues.


Air pollution induces changes in the oral mucosa and worsens periodontal disease
SDG 3
Air pollution induces changes in the oral mucosa and worsens periodontal disease

Research conducted on mice provides experimental evidence that exposure to PM2.5, a main component of urban air pollution, increases oxidative stress, intensifies inflammatory responses, and worsens the destruction of periodontal tissues.


Nanoparticle combines two strategies to speed up the healing of chronic wounds
SDG 3
Nanoparticle combines two strategies to speed up the healing of chronic wounds

A topical formulation brings together natural antioxidant and the genetic silencing of an enzyme that degrades cutaneous tissue. In laboratory tests, the treatment promoted full cell regeneration in just 72 hours.


Nanoparticle combines two strategies to speed up the healing of chronic wounds
SDG 3
Nanoparticle combines two strategies to speed up the healing of chronic wounds

A topical formulation brings together natural antioxidant and the genetic silencing of an enzyme that degrades cutaneous tissue. In laboratory tests, the treatment promoted full cell regeneration in just 72 hours.


New technique reveals on a large scale how thousands of proteins change shape and move
SDG 3, SDG 9
New technique reveals on a large scale how thousands of proteins change shape and move

Led by a Brazilian researcher, a study published in Nature shows that molecules with nearly identical three-dimensional structures can exhibit completely different behaviors over time.


Study seeks innovative therapies against COVID-19
SDG 3
Study seeks innovative therapies against COVID-19

A researcher affiliated with a FAPESP-funded center is studying monoclonal antibodies capable of neutralizing different variants of SARS-CoV-2.


Use of omega-3 and ASA has a similar effect to antibiotics against severe periodontitis
SDG 3
Use of omega-3 and ASA has a similar effect to antibiotics against severe periodontitis

Study shows that combining the two compounds with conventional treatment may be a promising alternative, reducing the need for antibiotics.


Mega-study analyzes the impact of gratitude interventions
SDG 3
Mega-study analyzes the impact of gratitude interventions

Research conducted in 34 countries compared six practices designed to foster gratitude with three control measures, observing variations in effects based on cultural differences.


Genetic testing changes the course of hereditary cancer in a family observed for 20 years
SDG 3
Genetic testing changes the course of hereditary cancer in a family observed for 20 years

A case report published in the journal CA: A Cancer Journal for Clinicians shows how genetic analysis and molecular biology studies helped confirm the diagnosis, guide preventive surgeries, and define personalized surveillance strategies across generations.


New vaccine strategy protects against chikungunya and could become a platform for combating other diseases
SDG 3
New vaccine strategy protects against chikungunya and could become a platform for combating other diseases

In tests conducted on mice, a single dose of the formulation containing genetically modified viruses protected the rodents against the disease.


News about research projects funded by FAPESP and articulated with the SDGs: