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FAPESP and the Sustainable Development Goals

News

SDG 3 Good Health and Well-being

News

SDG 3 Good Health and Well-being

People with Down syndrome have early neuroinflammation
SDG 3
People with Down syndrome have early neuroinflammation

Researchers at the University of São Paulo identify a new factor that explains the high prevalence of Alzheimer’s disease in older people with Down syndrome. The discovery paves the way for disease prevention strategies in this population.


Combination of quantum and classical computing supports early diagnosis of breast cancer
SDG 3, SDG 9
Combination of quantum and classical computing supports early diagnosis of breast cancer

Simple quantum-classical neural networks achieve good results in classifying lesions with fewer computational parameters. Scientists from São Paulo State University demonstrated a hybrid model at an international symposium.


Brazilian researchers warn that healthcare for transgender people is under threat
SDG 3, SDG 10
Brazilian researchers warn that healthcare for transgender people is under threat

Article published in Nature Medicine points to the risk of setbacks in research focused on this population. Experts question new rules in Brazil and other countries.


Geomagnetic disturbances caused by the Sun influence the occurrence of heart attacks, especially among women
SDG 3
Geomagnetic disturbances caused by the Sun influence the occurrence of heart attacks, especially among women

To reach this conclusion, Brazilian researchers cross-referenced data obtained from the local public health network with data from an indicator of variations in the Earth’s geomagnetic field. The study was published in the journal Communications Medicine.


Group creates tool to predict whether multiple sclerosis medication will be effective for patients
SDG 3
Group creates tool to predict whether multiple sclerosis medication will be effective for patients

Brazilian researchers, in partnership with French institutions, combine advanced cell image analysis technology and machine learning and discover a morphological marker linked to individuals who do not respond to natalizumab.


Super-resistant bacteria found in wild birds at a rehabilitation center on the coast of São Paulo state, Brazil
SDG 3
Super-resistant bacteria found in wild birds at a rehabilitation center on the coast of São Paulo state, Brazil

A vulture recently arrived at the Santos Municipal Orchid Garden and an owl living in captivity for ten years were colonized by antibiotic-resistant Escherichia coli.


Study identifies candidates for therapeutic targets in pediatric germ cell tumors
SDG 3
Study identifies candidates for therapeutic targets in pediatric germ cell tumors

Pioneering research conducted in São Paulo state (Brazil) shows how the immune system reacts to rare types of childhood cancer.


Plant-derived compound has antimicrobial and anti-inflammatory effects against periodontal disease
SDG 3
Plant-derived compound has antimicrobial and anti-inflammatory effects against periodontal disease

Morin-based powder, extracted from guava leaves, apple peel, and figs, can be slowly released with the help of polymers and serve as an alternative to antibiotics.


Microplastics may affect bone health
SDG 3
Microplastics may affect bone health

Brazilian researchers analyzed over 60 scientific articles on the subject and found that the materials negatively affect bone tissue.


Study recommends integrated risk assessment for zoonotic and vector-borne diseases
SDG 3
Study recommends integrated risk assessment for zoonotic and vector-borne diseases

A summary of published studies on the risk of emerging diseases shows that only 7.4% simultaneously consider hazard, exposure, and vulnerability to infection. These three components are essential for reliably and accurately assessing the risk of these diseases in the context of environmental change.


Green tea improves insulin sensitivity and glucose tolerance in obese mice
SDG 3
Green tea improves insulin sensitivity and glucose tolerance in obese mice

A study in an animal model analyzed the muscle metabolism of guinea pigs on a high-calorie diet. Ultimately, consumption of the plant extract increased the expression of genes associated with glucose uptake and the activity of an essential metabolic enzyme.


Research identifies immune response that controls Oropouche infection and prevents neurological damage
SDG 3
Research identifies immune response that controls Oropouche infection and prevents neurological damage

Study conducted on mice provides important information that may help in the treatment of the disease. Confirmations in Brazil have increased in recent years.


Early childhood poverty endangers the future of millions of Brazilian children
SDG 3, SDG 10
Early childhood poverty endangers the future of millions of Brazilian children

Bringing together studies by various experts, the book Science of Early Childhood highlights the importance of this period in people’s development and lives. It also warns of the far-reaching consequences of social inequality.


Study confirms that inactive parents contribute to sedentary behavior in their children
SDG 3
Study confirms that inactive parents contribute to sedentary behavior in their children

On the other hand, when parents maintain an active routine, their children are more likely to follow suit. According to research by São Paulo State University involving 182 children and adolescents aged 6 to 17, mothers’ influence in encouraging physical activity was more than twice that of fathers.


Variations in glucose levels may indicate severity of heart attack damage
SDG 3
Variations in glucose levels may indicate severity of heart attack damage

Results from research conducted in Brazil show that glycemic delta is associated with the size of the heart attack and the strength of heart contractions. Acute myocardial infarction is the leading cause of death in Brazil.


Protein deficiency during pregnancy and lactation may compromise sperm viability in offspring
SDG 3
Protein deficiency during pregnancy and lactation may compromise sperm viability in offspring

Research with rats has shown that a maternal diet lacking protein during these stages leads to changes in the structure and function of the epididymis, which would explain impairments in motility, viability, and sperm concentration in male offspring.


Ancestry and genetic variants influence the risk of colorectal cancer
SDG 3
Ancestry and genetic variants influence the risk of colorectal cancer

The disease is the third most common type of cancer in Brazil, excluding non-melanoma skin tumors. Between 5% and 10% of cases are hereditary.


New bacterium discovered in the Amazon is closely related to Andean species that causes human bartonellosis
SDG 3
New bacterium discovered in the Amazon is closely related to Andean species that causes human bartonellosis

This neglected disease, also known as Peruvian wart and Oroya fever, is caused by bacteria of the genus Bartonella and is transmitted by sand flies. DNA found in insects from a protected area in Brazil is similar to that of pathogenic species found in Peru. While there is still no evidence that the new bacterium causes disease, scientists warn that monitoring should continue.


Study points out that a synthetic molecule helps reduce visceral fat and improve sleep
SDG 3
Study points out that a synthetic molecule helps reduce visceral fat and improve sleep

Early-stage clinical trial reveals that peptide has potential to become a new tool for improving metabolic health and sleep quality in overweight adults; study involved scientists from Brazil, Israel and the United States.


Study reveals possible strategy for fighting aggressive brain cancer
SDG 3
Study reveals possible strategy for fighting aggressive brain cancer

International team of researchers discovered that high levels of an enzyme called PRDX6 are associated with a subtype of neuroblastoma; animal studies showed that inhibiting the molecule caused a reduction in tumors.


SARS-CoV-2 infects testicular cells and uses cellular machinery to replicate and form
SDG 3
SARS-CoV-2 infects testicular cells and uses cellular machinery to replicate and form

Research conducted on mice revealed that the COVID-19 virus uses cells responsible for testosterone production to replicate, thereby interfering with lipid metabolism. This helps explain the drop in testosterone and possibly cholesterol in patients with severe cases of the disease.


Vaccine against Zika virus shows promising results in tests with mice
SDG 3
Vaccine against Zika virus shows promising results in tests with mice

The vaccine is being developed by researchers at the University of São Paulo and is based on technology known as “virus-like particles” (VLPs), which does not use genetic material from the pathogen.


Sarcopenia is better for assessing the risk of death in older adults than frailty syndrome
SDG 3
Sarcopenia is better for assessing the risk of death in older adults than frailty syndrome

This is the conclusion of a study that evaluated data from 4,500 people who were followed for 14 years. The results are helpful in clinical practice and for screening patients at risk, eliminating the need for complicated tests.


Brazilian company develops sustainable alternative to antibiotics for livestock
SDG 3, SDG 9, SDG 12
Brazilian company develops sustainable alternative to antibiotics for livestock

The startup uses bacteriophages to prevent mastitis in dairy cows and reduce the use of conventional drugs.


Laser therapy enhances treatment of fungus resistant to conventional medication
SDG 3
Laser therapy enhances treatment of fungus resistant to conventional medication

Researchers at a FAPESP-supported research center have managed to reduce Candida albicans’ resistance to fungicides by incorporating photodynamic inactivation techniques into the treatment. The results of the study indicate that the technology can be used in both human healthcare and the prevention of food contamination.


News about research projects funded by FAPESP and articulated with the SDGs: