More than 1,000 Brazilian volunteers immunized with the CoronaVac vaccine were assessed by researchers at the University of São Paulo. Those who were active for at least 150 minutes per week without long sedentary periods produced more antibodies against SARS-CoV-2.
A study conducted by researchers at the Center for Cell-Based Therapy in São Paulo state, Brazil, identified a genetic signature that can be used to predict whether patients should be submitted to radiation therapy.
Correlating whole-genome sequencing with epidemiological data for the city of São José do Rio Preto in Brazil, researchers show that severe COVID-19 and deaths from the disease rose sharply when the variant became prevalent in the region. A two-week lockdown and vaccination of the elderly averted a collapse of the health system.
A study published in Nature Medicine evaluated individuals before and after taking CoronaVac. Based on the results, researchers at the University of São Paulo’s Medical School are testing novel strategies such as suspending treatment one or two weeks before vaccination.
Outbreaks at two care homes in São Paulo state (Brazil) show that even people who have been vaccinated with one dose of the AstraZeneca vaccine or two doses of CoronaVac can transmit the virus. The cases were asymptomatic or mild and did not require hospitalization, but underscore the importance of rapidly vaccinating the entire population while continuing to require face coverings and social distancing even for those who have been vaccinated.
A webinar held by FAPESP featured researchers from Brazil and Germany whose findings offer clues as to how SARS-CoV-2 invades the central nervous system and which cells are most affected.
Brazilian researchers coupled the molecule with a protein that binds to SARS-CoV-2. The presence of antibodies against the virus in the sample is confirmed by light emission.
Developed by startup In Situ from stem cells and a hydrogel, the product is bioprinted and placed lightly on the skin.
Non-invasive method uses samples of saliva or other body fluids. The diagnosis can be obtained by means of computational techniques for visualizing data and machine learning.
Study at the Federal University of São Paulo developed a recipe combining chickpea flour and psyllium, a plant-derived soluble fiber. The product is nourishing and rated highly by consumers in qualitative surveys.
Researchers compared data for pregnant women in Rio de Janeiro and Manaus who were infected by zika virus in 2015-16. Factors that influenced the risk of fetal malformation were the high zika attack rate in the area and being infected in the first trimester of pregnancy.
Based on data for 344 volunteers, Brazilian researchers compared the physical and mental health benefits of workouts led in person by a fitness instructor, unsupervised online sessions, and classes supervised remotely via video call. Gradually increasing intensity was associated with improvements in mental health.
A project led by researchers at Getúlio Vargas Foundation in Brazil and the University of Michigan in the US produced a detailed analysis of the effects of public policies and government decisions on the response to COVID-19, highlighting the factors that influenced its success or failure in many countries and regions around the world.
The study was conducted in the city of São Paulo, with over 2,000 participants who were active or retired staff of the University of São Paulo and enrolled in the Brazilian Longitudinal Study of Adult Health (ELSA-Brazil). The researchers say the city has one of the highest prevalence rates of psychiatric disorders in the world.
The initiative is being implemented as a partnership between local government, DASA Laboratories and FAPESP.
The platform holds more than 50 million datasets from 800,000 patients in Brazil and has registered some 4,000 downloads by users in 36 countries.
In an online seminar organized by FAPESP, researchers in Brazil and the United States presented preliminary results of studies on mental health and quality of life among survivors of COVID-19 up to six months after discharge from hospital.
Tests performed by Brazilian researchers after the first 16 weeks of COVID-19-induced confinement showed loss of muscle strength and diminished aerobic capacity, as well as an increase in cholesterol and glycated hemoglobin, both of which are risk factors for metabolic disorders.
Butantan Institute produces CoronaVac and is testing two new vaccines. Four projects are under way at the University of São Paulo, and two at startups supported by FAPESP’s PIPE innovation funding program.
An online study involving 154 volunteers measured the importance of visual cues to communication for people with normal hearing and hearing loss.
A study conducted at São Paulo State University shows that mathematical models used to describe the physical behavior of magnetic materials can also be used to describe the spread of the disease.
Researchers at the University of São Paulo conducted experiments with blood plasma from 60 volunteers infected in 2020 by SARS-CoV-2 lineage B.1.1.28. In 84% of cases, antibodies in the samples neutralized the Gamma variant in cultured cells.
The presence of Candida auris in a hospital in Salvador, Bahia, was confirmed at end-2020 and reported in an article in the Journal of Fungi. The fungus can cause a lethal invasive disease and is ringing alarm bells because of the speed with which it develops drug resistance.
An Anglo-Brazilian research center analyzed samples from blood donors tested for antibodies against the novel coronavirus.