Fapesp

FAPESP and the Sustainable Development Goals

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SDG 3 Good Health and Well-being

News

SDG 3 Good Health and Well-being

Sanitized ready-to-eat salad may contain disease-causing bacteria
SDG 3
Sanitized ready-to-eat salad may contain disease-causing bacteria

A review of research on minimally processed vegetables highlights cases of unsatisfactory microbiological safety and calls for best practice assurance throughout the supply chain.


In Situ Cell Therapy wins eAwards Brazil 2023
SDG 3, SDG 9
In Situ Cell Therapy wins eAwards Brazil 2023

With FAPESP’s support, the startup developed a smart biodressing produced by 3D printing and designed to accelerate skin wound healing. It will compete for a Global eAward in October.


Study reveals how deep brain stimulation helps control epilepsy
SDG 3
Study reveals how deep brain stimulation helps control epilepsy

Experiments with rats at the Federal University of São Paulo suggest that the technique promotes reprogramming of the neurons affected by the disease, making them return to a normal state and interrupting seizures. Increased production of adenosine appears to play a key role in the process.


Sleep apnea accelerates aging, but use of breathing therapy method can mitigate the problem
SDG 3
Sleep apnea accelerates aging, but use of breathing therapy method can mitigate the problem

In a study involving 46 volunteers, researchers at the Federal University of São Paulo found that telomere shortening, a biomarker of cellular aging, accelerated in untreated obstructive sleep apnea patients, whereas continuous positive airway pressure attenuated the damage.


Build-up of abdominal fat increases risk of vitamin D insufficiency and deficiency, study shows
SDG 3
Build-up of abdominal fat increases risk of vitamin D insufficiency and deficiency, study shows

A collaborative study by Brazilian and British researchers shows for the first time that obesity can cause a lack of vitamin D and not the other way around. The risk of vitamin D insufficiency and deficiency in subjects with abdominal obesity was 36% and 64% higher respectively than in those without.


Study proposes use of artificial intelligence to diagnose autism spectrum disorder
SDG 3
Study proposes use of artificial intelligence to diagnose autism spectrum disorder

Researchers used magnetic resonance imaging to train a machine learning algorithm to help diagnose autism. The study involved physicists, statisticians, physicians and neuroscientists from centers in Brazil, France and Germany.


Exercise is beneficial even in a polluted environment, study shows
SDG 3
Exercise is beneficial even in a polluted environment, study shows

Researchers at the University of São Paulo analyzed inflammatory markers in cyclists who trained regularly and had been exposed to traffic-related pollution. The results of the experiment, which was conducted in São Paulo city, are published in the American Journal of Physiology.


Cross-border consortium investigates long-term effects of pandemic on children and young adults
SDG 3
Cross-border consortium investigates long-term effects of pandemic on children and young adults

The aim of the study is to understand the strategies used by children and young people in low-income households to adapt to the public health crisis and economic hardship in the UK, South Africa and Brazil.


Co-infection by novel species of parasite is confirmed in visceral leishmaniasis patient
SDG 3
Co-infection by novel species of parasite is confirmed in visceral leishmaniasis patient

Genome sequencing of clinical samples from a child hospitalized in Aracaju, the capital of Sergipe state (Brazil), revealed the simultaneous presence of the protozoan Leishmania infantum and an as-yet unnamed parasite belonging to the genus Crithidia, identified earlier in a fatal case of visceral leishmaniasis in the same region.


Innovation to treat skin cancer will be used by Brazil’s public health clinics
SDG 3, SDG 9
Innovation to treat skin cancer will be used by Brazil’s public health clinics

Photodynamic therapy developed by the Center for Research in Optics and Photonics, which is supported by FAPESP, has been recommended by Brazil’s federal body responsible for including novel healthcare technologies in the national health service.


Three out of every ten meals ordered from the main food delivery app in Brazil come from dark kitchens
SDG 3, SDG 12
Three out of every ten meals ordered from the main food delivery app in Brazil come from dark kitchens

The first-ever study of dark kitchens conducted in Brazil collected data on 22,520 establishments located in three cities in São Paulo state and listed by iFood. An article on the study offers a profile of these delivery-only restaurants, which proliferated during the pandemic.


Research with Brazilian participation is first to create models of bovine embryos
SDG 3, SDG 9
Research with Brazilian participation is first to create models of bovine embryos

The results pave the way for breeding of cattle with selected traits. Preliminary work findings for human embryo models recently published by international groups could contribute to the understanding of congenital defects and early pregnancy loss.


Compound reduced inflammation in COVID-19-infected mice without compromising immune response to virus
SDG 3
Compound reduced inflammation in COVID-19-infected mice without compromising immune response to virus

A team affiliated with a FAPESP-supported research center showed in mice that molecules capable of preventing the peptide C5a from binding to its cellular receptor helped prevent lung damage and other complications typical of severe COVID-19.


Consumption of soluble dietary fiber favors renewal of intestinal epithelial cells, study shows
SDG 3
Consumption of soluble dietary fiber favors renewal of intestinal epithelial cells, study shows

In experiments conducted at the State University of Campinas (Brazil), intestinal epithelial stem cells proliferated more in mice fed an inulin-rich diet than in mice given insoluble fiber. The study also showed that the beneficial effects depended on interaction with gut microbiota.


SARS-CoV-2 infects liver, stimulating glucose production and contributing to severe form of COVID-19
SDG 3
SARS-CoV-2 infects liver, stimulating glucose production and contributing to severe form of COVID-19

A study conducted at the University of São Paulo and reported in PNAS explains hyperglycemia in hospitalized patients and shows how SARS-CoV-2 causes symptoms similar to those of diabetes.


Novel targets identified for treatment of schistosomiasis
SDG 3
Novel targets identified for treatment of schistosomiasis

Researchers at Butantan Institute in São Paulo, Brazil, discovered that survival of the parasitic worm that causes the disease depends on expression of a specific type of RNA. In animal trials, inhibition of the molecule interrupted the infection.


Adipose tissue hormone protects cells that secrete insulin and reverses damage associated with obesity
SDG 3
Adipose tissue hormone protects cells that secrete insulin and reverses damage associated with obesity

Researchers at the University of São Paulo observed the effects of adiponectin in trials involving blood samples from lean and obese subjects. The discovery points to novel routes to treatment for type 2 diabetes and related dysfunctions.


Mortality rate from <i>Candida</i> infections remains high in Brazil, despite therapeutic advances
SDG 3
Mortality rate from <i>Candida</i> infections remains high in Brazil, despite therapeutic advances

A study conducted at the Federal University of São Paulo shows that 20% of patients with bloodstream infections are not treated, and at least half of those treated die. Diagnostic techniques must improve, the authors warn.


Novel compound combats drug-resistant fungi when combined with commercially available medications
SDG 3
Novel compound combats drug-resistant fungi when combined with commercially available medications

Combinations of antifungals with brilacidin, a drug undergoing clinical trials for other diseases, cleared up lung infections in animals. On its own, the candidate drug treated a fungal disease of the cornea that affects millions of people worldwide.


Compound produced by invasive marine coral eliminates parasite that causes Chagas disease
SDG 3, SDG 14
Compound produced by invasive marine coral eliminates parasite that causes Chagas disease

Trials involving mammalian cells were conducted by researchers in São Paulo state, Brazil. Although it endangers biodiversity along much of the coast, sun coral could be an ally in combating Chagas disease, which affects 7 million people worldwide and lacks effective treatment.


Study suggests resistance training can prevent or delay Alzheimer’s disease
SDG 3
Study suggests resistance training can prevent or delay Alzheimer’s disease

Experiments involving mice and conducted by Brazilian researchers showed four weeks of training with weights to be sufficient to reverse behavioral and physical alterations characteristic of the disease.


COVID-19 sequelae are the highlights of a neuroscience conference at the State University of Campinas
SDG 3
COVID-19 sequelae are the highlights of a neuroscience conference at the State University of Campinas

Brazilian researchers analyzed data from MRI scans and various tests to detect biological alterations linked to the neurological symptoms most reported by patients, especially anxiety, depression, sleepiness and fatigue. The latest results were presented to the ninth edition of BRAINN Congress.


Propolis improves immunity, reduces free radicals and attenuates chronic inflammation in HIV patients
SDG 3
Propolis improves immunity, reduces free radicals and attenuates chronic inflammation in HIV patients

A study of 40 asymptomatic subjects living with HIV conducted at São Paulo State University showed that a daily dose of 500 mg was safe and helped combat premature aging.


Laser therapy is most effective treatment for tinnitus, study finds
SDG 3
Laser therapy is most effective treatment for tinnitus, study finds

Brazilian researchers compared the therapies used most frequently for tinnitus, which affects some 750 million worldwide.


Study identifies intracellular protein that can block inflammation in autoimmune diseases
SDG 3
Study identifies intracellular protein that can block inflammation in autoimmune diseases

The discovery, led by researchers at a FAPESP-supported center, could lead to novel treatments for autoimmune diseases.


News about research projects funded by FAPESP and articulated with the SDGs: