Developed at the University of São Paulo, the device permits corrections to the dosage of the analgesic to improve its efficacy according to the patient’s profile and avoid toxic side effects or overdose.
The device, produced by ordinary 3D printing and capable of being miniaturized, detects levels of the protein PARK7/DJ-1, which is associated with the disease. The study used samples of blood serum and cerebrospinal fluid.
A study by a group at the University of São Paulo reported in a scientific journal involved the construction of a database and models. Preliminary results are described in the article.
Deletion of two genes, which in mice attenuated the action of the bacteria, made the immune response more exacerbated in broiler chicks. The findings reinforce the need for animal health and hygiene measures throughout the poultry production chain.
The finding is from a longitudinal study conducted in Brazil. Analyzing data for high school students aged 13-18, it concluded that the problem affects girls more than boys and is associated with physical inactivity and low academic achievement.
The center will be hosted by the Federal University of Ceará and will focus on the use of the Internet of Things, big data, digital transformation and cutting-edge technology in prevention, diagnosis and low-cost therapies.
Addition of rosmarinic acid at a mere 0.1% reduced the amount of sunscreen needed to protect the skin, increased the sun protection factor by more than 41% and combined photoprotection with antioxidant activity. The innovation would reduce the volume of chemical substances discharged into the environment.
This conclusion, presented by Brazilian researchers in the journal Scientific Reports, is based on a systematic review of clinical trials held to investigate the effect of strength training on blood pressure in hypertensive patients. All age groups benefited, but the positive effects were most evident in patients aged 50 or less.
With the support of FAPESP and Banco Industrial do Brasil, the National Center for Research and Innovation in Mental Health (CISM) was launched at an event held on March 15.
Experiments involving nematode worms conducted by researchers at the University of São Paulo showed that the benefits of physical activity to muscles are directly linked to processes occurring in mitochondria, the organelles that make energy for cells. Their findings offer possible routes for drug development.
In a study conducted in São Paulo, Brazil, exercise training increased connectivity between the hypothalamus and sensory regions, accelerating satiety, for example.
Analysis conducted in Spain used a methodology developed by researchers at the State University of Campinas to detect many toxins simultaneously.
A study in rats analyzed neural rhythm in the prefrontal cortex and hippocampus with machine learning techniques. The results could guide future personalized treatments for psychiatric disorders.
The aim of the study was to analyze the virulence and antimicrobial resistance profile of the main agent of urinary tract infections.
Fatigue, breathlessness and other symptoms that may persist months after recovery from the infection may both favor sedentarism and be more frequent as a result of an inactive lifestyle, according to findings described by researchers at the University of São Paulo in an article in Scientific Reports.
Significant changes in gut microbiota were observed in 42 men with coronary artery disease after they took 250 ml of red wine per day for five days a week over a period of three weeks.
The study involved 28 volunteers diagnosed with sarcopenia, which is characterized by loss of muscle mass and strength.
Researchers followed 286 volunteers during a wave of COVID-19 in the Northeast region of Brazil in the first quarter of 2022. The number of cases fell among those who had been vaccinated with three doses, and they had more neutralizing antibodies than subjects who had not completed the vaccination scheme even when previously infected.
An article by researchers at the Federal University of São Paulo argues that the analysis should consider not just the quantity but also the size and shape of plastic particles in water samples, as these variables influence the impact of plastic pollution on ecosystems.
The novel material was synthesized at the Center for Development of Functional Materials. The aim of the study was to combat the contamination caused by inappropriate disposal of pesticides and pharmaceuticals.
Brazilian researchers conducted preclinical trials involving mice to find the ideal dose and administration regime. The results suggest high daily doses of the probiotic are needed to obtain the benefit.
In a Brazilian study involving 800 children, researchers found that extended breastfeeding protects the baby’s teeth as long as it is not given sugary food.
A study conducted at the University of São Paulo provides knowledge for use in diagnosing and treating chronic fatigue syndrome, which affects 10%-20% of patients who recover from COVID-19.
Cetuximab is one of the few drugs approved for this type of cancer, but it is expensive and effective only for 40% of patients. An article in the journal Cells describes molecular alterations observed in tumor cells that indicate resistance to the drug, paving the way to the development of a predictive test.
Based on an analysis of data for nearly 1,000 participants in the English Longitudinal Study of Ageing born in the 1950s and 1960s, researchers concluded that children’s relationships with parents influence longevity, although the impact is different for men and women.
