Fapesp

FAPESP and the Sustainable Development Goals

News

SDG 3 Good Health and Well-being

News

SDG 3 Good Health and Well-being

Clinical and genetic data may help predict responses to psychosis treatments
SDG 3
Clinical and genetic data may help predict responses to psychosis treatments

In a study of 141 patients, researchers at the Federal University of São Paulo and collaborators evaluated different models to predict which patients would benefit from risperidone treatment.


Study points to contraindications for intermittent fasting
SDG 3
Study points to contraindications for intermittent fasting

In mice, researchers observed increased intestinal stem cell proliferation and organ regeneration in the post-fasting period. However, depending on the diet and genetic profile, this can increase the risk of tumors.


Study reveals role of redox protein in hypertension
SDG 3
Study reveals role of redox protein in hypertension

Discovery at the Center for Redox Processes in Biomedicine showed positive results in hypertensive rats and therapeutic potential.


Cell phones are used to determine the origin and authenticity of indigenous coffees in the Amazon
SDG 3, SDG 9
Cell phones are used to determine the origin and authenticity of indigenous coffees in the Amazon

The method is part of a series of international studies on the Canephora species published by Brazilians and can be adapted to identify “fake coffees”.


Study identifies genes that can predict response to immunotherapy in melanoma patients
SDG 3
Study identifies genes that can predict response to immunotherapy in melanoma patients

Brazilian researchers develop precision tool that can predict immunotherapy treatment failure, with the potential to personalize therapies and reduce healthcare costs.


Studies confirm influence of country of origin on trust in COVID-19 vaccines
SDG 3
Studies confirm influence of country of origin on trust in COVID-19 vaccines

During the pandemic, a preference for domestic vaccines or those from countries such as the United States, Germany, and the United Kingdom was observed for the first time. This phenomenon, known in marketing as the country of origin effect, is usually associated with products that require consumer research before purchase or that have a long tradition in certain countries, such as Swiss chocolates. However, it had never been linked to free vaccines.


FAPESP-supported research center publishes article on non-invasive brain stimulation techniques
SDG 3
FAPESP-supported research center publishes article on non-invasive brain stimulation techniques

Three promising brain stimulation methods used in medical practice and academic research.


AI-based tool can ‘measure’ cancer aggressiveness and paves the way for new therapies
SDG 3
AI-based tool can ‘measure’ cancer aggressiveness and paves the way for new therapies

Developed at the University of São Paulo, the model uses protein expression to create a stemness index that analyzes the similarity of tumors to pluripotent stem cells. The article was published in Cell Genomics.


Researchers at the University of São Paulo create more complex mini-brains to study the key to healthy aging
SDG 3
Researchers at the University of São Paulo create more complex mini-brains to study the key to healthy aging

Organoids were developed from the blood cells of centenarians who are part of a project conducted at the Human Genome and Stem Cell Research Center to discover genes that protect the brain from the effects of aging.


Group is investigating biomarkers for the early detection of Alzheimer’s disease
SDG 3
Group is investigating biomarkers for the early detection of Alzheimer’s disease

Based on the analysis of the genotypes of 500 volunteers, the research project aims to develop a panel of prognostic biomarkers and differentiate Alzheimer’s disease from other types of dementia using blood tests.


Substances isolated from marine sponges show potential for treating malaria
SDG 3
Substances isolated from marine sponges show potential for treating malaria

In pre-clinical tests conducted at the University of São Paulo, compounds called batzelladins were effective even against strains of Plasmodium that are resistant to conventional antimalarial drugs.


Reusing sunflower seed flour can make bread more protein-packed and rich in antioxidants
SDG 3, SDG 12
Reusing sunflower seed flour can make bread more protein-packed and rich in antioxidants

A study by Brazilian scientists shows that a by-product of industrial sunflower oil extraction can be used to produce functional breads with high nutritional value.


New center will study endemic fungal diseases in Latin America
SDG 3, SDG 17
New center will study endemic fungal diseases in Latin America

FAPESP will begin supporting the Latin American Center for Medical Mycology, a global network of laboratories led by the University of Exeter in the United Kingdom, which also has a unit in South Africa and will soon open another in Asia. Over five years, the foundation will contribute approximately £ 750,000, while the British institution will invest an additional £ 1 million.


Overtraining: the cause of symptoms caused by excessive physical exercise has been discovered
SDG 3
Overtraining: the cause of symptoms caused by excessive physical exercise has been discovered

In tests with rodents, researchers from the State University of Campinas and their collaborators found that hyperactivation of the PARP1 protein after exhaustive training was associated with decreased performance, fatigue, and behavioral symptoms of overtraining. Animals treated with a drug that inhibits the molecule’s activity did not exhibit the condition.


Sensory-motor activity protocol increases reading speed of children with dyslexia
SDG 3
Sensory-motor activity protocol increases reading speed of children with dyslexia

A pilot intervention project involving playful activities that engaged motor skills and cognition showed promising results in improving eye movements and reading speed in eleven children with dyslexia.


Fishermen in Maceió, Brazil, have higher-than-average mercury levels
SDG 3
Fishermen in Maceió, Brazil, have higher-than-average mercury levels

Blood and urine analyses of the population living in the Mundaú lagoon complex revealed a greater presence of chemical contaminants and metabolic alterations that can exacerbate chronic diseases, such as diabetes and hypertension. These results underscore the need to monitor the health of the inhabitants and control the sources of contamination.


Researchers develop ‘vegan meat’ based on sunflower flour
SDG 3
Researchers develop ‘vegan meat’ based on sunflower flour

The ingredient, extracted from the plant’s seeds, is a good source of protein and has a neutral flavor and aroma, making it easy to use in food products.


Researchers identify protein essential for balancing bone tissue
SDG 3
Researchers identify protein essential for balancing bone tissue

Findings published in the International Journal of Biological Macromolecules could guide studies aimed at treating diseases such as osteoporosis.


Research reveals how hormone accelerates fat burning and promotes weight loss in obese mice
SDG 3
Research reveals how hormone accelerates fat burning and promotes weight loss in obese mice

An experiment conducted at the State University of Campinas showed that FGF19, produced in the intestine, acts on specific regions of the brain, causing the body to burn energy to produce heat; the discovery paves the way for new drugs.


Article presents innovative drug for controlling weight and blood sugar
SDG 3
Article presents innovative drug for controlling weight and blood sugar

In animal tests, the molecule developed in South America has been shown to prevent fat accumulation and treat existing obesity and associated metabolic disorders. Initial human studies have confirmed the safety of the compound.


Research reveals specific type of rare genetic variation linked to obsessive-compulsive disorder
SDG 3
Research reveals specific type of rare genetic variation linked to obsessive-compulsive disorder

The study compared data from patients and healthy individuals from Brazil, Canada, and the United States. The results help paint a clearer picture of how genetics influences the development of OCD.


Amazon scorpion toxin kills breast cancer cells
SDG 3
Amazon scorpion toxin kills breast cancer cells

Researchers from the University of São Paulo have identified a molecule in arachnid venom that acts similarly to a commonly used chemotherapy drug for treating the disease; preliminary results of the study were presented at FAPESP Week France.


Study identifies molecule in stingless bee propolis that can kill dengue mosquito larvae
SDG 3
Study identifies molecule in stingless bee propolis that can kill dengue mosquito larvae

Researchers have found a substance in propolis from bees native to Brazil that kills 90% to 100% of Aedes aegypti larvae. The compound, found in pine sap, is likely enhanced by insect processing and has the potential to help combat mosquitoes that transmit arboviruses.


Researchers from Brazil and France are set to test new cell therapy for cancer
SDG 3
Researchers from Brazil and France are set to test new cell therapy for cancer

Scientists from the Curie Institute and the University of São Paulo are about to conduct a clinical study to evaluate the safety and efficacy of a new CAR-T cell-based immunotherapy for patients with oculocerebral lymphoma; the project was presented at FAPESP Week in Toulouse.


Machine learning can predict which babies will be born with low birth weights
SDG 3
Machine learning can predict which babies will be born with low birth weights

The evaluation of predictive models for low birth weight cases was based on data from a population study of over 1,500 pregnant women in the city of Araraquara in the state of São Paulo, Brazil. Early identification of the problem is crucial for effective intervention.


News about research projects funded by FAPESP and articulated with the SDGs: