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FAPESP and the Sustainable Development Goals

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SDG 3 Good Health and Well-being

News

SDG 3 Good Health and Well-being

Study confirms benefits of auricular acupuncture to treat depression
SDG 3
Study confirms benefits of auricular acupuncture to treat depression

For three months, Brazilian researchers tracked 74 patients submitted to 12 sessions lasting 15 minutes each and observed remission of symptoms. The ancient Chinese practice had no side effects, according to an article on the study published in JAMA Network Open.


Analysis of photographs of building facades can help map high-risk urban areas for dengue
SDG 3
Analysis of photographs of building facades can help map high-risk urban areas for dengue

The methodology was developed by Brazilian and British researchers, who tested it in Campinas, a large city in São Paulo state. Its aim is to optimize monitoring and combating the mosquito Aedes aegypti.


Factors that increase risk of frailty in old age are different in men and women
SDG 3
Factors that increase risk of frailty in old age are different in men and women

Brazilian and British researchers analyzed data for 1,747 older participants tracked by ELSA over a period of 12 years, and mapped the different routes that can lead to a negative outcome. They advocate use of their findings by policymakers.


Novel treatment strategy reduces inflammation and cardiometabolic risk in adolescents with obesity
SDG 3
Novel treatment strategy reduces inflammation and cardiometabolic risk in adolescents with obesity

An interdisciplinary approach tested at the Federal University of São Paulo combined clinical, nutritional, psychological and exercise counseling. The intervention involved remote and in-person sessions, favoring adherence and lowering the cost to the health system.


Nanoparticles containing natural substance treat visceral leishmaniasis with scant side effects
SDG 3
Nanoparticles containing natural substance treat visceral leishmaniasis with scant side effects

In animal tests conducted at São Paulo State University (UNESP), the strategy reduced spleen and liver parasite numbers by 99.9%.


Study highlights importance of genetic sequencing to diagnosis of growth disorders
SDG 3
Study highlights importance of genetic sequencing to diagnosis of growth disorders

Researchers at the University of São Paulo analyzed data from 115 children who suffered from conditions considered syndromic (with several associated symptoms) and found a high incidence of overlapping genetic alterations. They argue that identification of genetic mutations can make diagnosis and treatment more accurate.


Rare case of opossum infected by rabies sounds alarm regarding circulation of this virus in urban environments
SDG 3
Rare case of opossum infected by rabies sounds alarm regarding circulation of this virus in urban environments

The opossum was found dead in a park in the center of Campinas, a large city in São Paulo state (Brazil), with the same viral variant as fruit-eating bats. These mammals are regularly detected in cities, where they are often attacked by dogs, so they can be considered sentinel species for infectious disease surveillance.


An important molecular pathway for control of aging is discovered
SDG 3
An important molecular pathway for control of aging is discovered

Through experiments in roundworms of the species C. elegans, scientists at a FAPESP-supported research center showed that lifespan is reduced when RNA transfer between cells in different tissues is dysregulated.


Overconsumption of fructose by parents increases risk of cardiometabolic disease in offspring, study shows
SDG 3
Overconsumption of fructose by parents increases risk of cardiometabolic disease in offspring, study shows

Blood pressure rose in offspring born to high-fructose rats, and physiological regulation of their cardiovascular system was impaired. High-fructose syrup is widely used as a sweetener by the food and beverage industry.


Prior zika infection increases risk of subsequent severe dengue and hospitalization, study concludes
SDG 3
Prior zika infection increases risk of subsequent severe dengue and hospitalization, study concludes

A study led by Brazilian researchers suggests that the mechanism that exacerbates dengue infection following a case of zika differs from that acting on second-time dengue patients. The finding is relevant to the development of a zika vaccine.


Scientists discover that a protein associated with neurodegenerative diseases is also linked to childhood brain cancer
SDG 3
Scientists discover that a protein associated with neurodegenerative diseases is also linked to childhood brain cancer

A study conducted at a FAPESP-supported research center discovered a link between the protein VAPB and tumor cell proliferation in medulloblastoma, one of the most common and aggressive brain tumors in children.


Study demonstrates antitumor action of substance present in Brazilian green propolis
SDG 3
Study demonstrates antitumor action of substance present in Brazilian green propolis

The analysis compared the effects of artepillin C on healthy cells and cancer cells, as well as the effects on its efficacy of variations in the medium’s pH.


Study reveals mechanism that aggravates tuberculosis and reduces survival rates
SDG 3
Study reveals mechanism that aggravates tuberculosis and reduces survival rates

CD4+ T cells play an important role in the immune response to pulmonary infections, but excessive amounts can damage the lungs. In experiments with mice, researchers at the University of São Paulo discovered what leads to this exacerbated response.


Butantan Institute’s dengue vaccine protects 79.6% of those vaccinated, study shows
SDG 3
Butantan Institute’s dengue vaccine protects 79.6% of those vaccinated, study shows

Data from the Phase 3 clinical trial was published on February 1st in The New England Journal of Medicine. The vaccine is safe for both participants who have had dengue and those who have never been exposed to the virus before.


Biodegradable sensor monitors levels of pesticides via direct contact with surface of fruit and vegetables
SDG 3, SDG 12
Biodegradable sensor monitors levels of pesticides via direct contact with surface of fruit and vegetables

Developed by a team of Brazilian researchers, the device is made of plant-based material with little environmental impact, and detects pesticides in a few minutes, helping to certify food safety.


Cancer: mortality is higher among Black people in Barretos (São Paulo state, Brazil) and among White people in São Paulo city
SDG 3, SDG 10
Cancer: mortality is higher among Black people in Barretos (São Paulo state, Brazil) and among White people in São Paulo city

In 18 cities of the Barretos region, where the proportion of Black people in the population is smaller, cancer kills more members of this ethnic group, whereas in the capital of the same state, it kills more White people, according to a study that compares cancer mortality rates and points to ways of reducing inequalities in diagnosis and treatment.


Study helps explain why stress in adolescence can lead to predisposition to mental illness in adulthood
SDG 3
Study helps explain why stress in adolescence can lead to predisposition to mental illness in adulthood

In experiments with rats, researchers at the University of São Paulo analyzed brain tissue and detected alterations in genes associated with energy metabolism.


Study explains why protein-poor diet during pregnancy increases risk of prostate cancer in offspring
SDG 3
Study explains why protein-poor diet during pregnancy increases risk of prostate cancer in offspring

In experiments with rats, researchers at São Paulo State University detected changes in the expression of more than 700 genes in offspring. One of these genes is known to be associated with prostate cancer.


Study of gigantism in whales provides clues to genomic mechanism involved in tumor suppression
SDG 3, SDG 14
Study of gigantism in whales provides clues to genomic mechanism involved in tumor suppression

Some species of cetacean are up to 4 meters in length, while others reach 30 meters. According to researchers at the State University of Campinas, genes that favor the colossal growth of these mammals also inhibit the development of cancer.


Cases of chikungunya and zika fall in Brazil, but most risk clusters exhibit an upward trend
SDG 3
Cases of chikungunya and zika fall in Brazil, but most risk clusters exhibit an upward trend

Researchers at the University of São Paulo and São Paulo state’s Center for Epidemiological Surveillance observed spatial and temporal patterns of occurrence and co-occurrence for the two arboviral diseases in all Brazilian municipalities, alongside the influence of environmental and socio-economic factors.


A single session of aerobic exercise improves blood pressure in rheumatoid arthritis patients
SDG 3
A single session of aerobic exercise improves blood pressure in rheumatoid arthritis patients

A study involving 20 women with rheumatoid arthritis and high blood pressure demonstrates the benefits of walking at moderate speed for 30 minutes even after tests that simulate stressful situations and tend to raise blood pressure.


Intravaginal sponge can make treatment of candidiasis more comfortable and effective
SDG 3
Intravaginal sponge can make treatment of candidiasis more comfortable and effective

The device is under preclinical trials; the sponge is made of soft, biodegradable material and releases medication slowly into the organism.


Startup develops rapid test to help detect cervical cancer
SDG 3, SDG 9
Startup develops rapid test to help detect cervical cancer

The kit is designed to be used for screening. If the result is negative, it should be repeated a year later. If positive, the individual should see a specialist.


Growth hormone influences regulation of anxiety via a specific group of neurons
SDG 3
Growth hormone influences regulation of anxiety via a specific group of neurons

Researchers at the University of São Paulo identified in mice the neurons associated with the anxiolytic effect of growth hormone. Their discovery paves the way for the development of novel classes of medications for neuropsychiatric disorders.


Brazilian researchers discover two novel peptides with biotechnological potential in snake venom
SDG 3
Brazilian researchers discover two novel peptides with biotechnological potential in snake venom

Fragments of hemorrhagic toxins that may help treat high blood pressure were found in the venom of the pit viper Cotiara, which inhabits the South of Brazil, and that of the South American bushmaster, a denizen of tropical rainforests. The molecules might one day be used in drugs with fewer adverse side effects.


News about research projects funded by FAPESP and articulated with the SDGs: