Tested in mice with genetically induced arthritis, the substance decreased the area affected, reduced local swelling, and assuaged the pain associated with the inflammatory process.
Autopsies performed on COVID-19 patients treated at the largest hospital complex in Latin America show that some died mainly as a result of cardiovascular alterations.
The largest database of plant viruses in Brazil serves as a tool for researchers, growers and policymakers.
Researchers at the Optics and Photonics Research Center, supported by FAPESP, advocate the technique as an additional treatment for patients with the disease.
Researchers from Brazil, Mexico, Nigeria and the US took part in a webinar organized by FAPESP to discuss privacy and data security and how people’s behavior shapes the pandemic
Study determined how the disease was transmitted using genomic data for SARS-CoV-2 obtained by sequencing almost 500 viral isolates from Brazilian patients and cross-referencing this with air travel data and deaths from the disease in the period.
Researchers have correlated information on drugs, genes and diseases to identify potential candidates for psychiatric and neurological treatment. The methodology they developed will be used to search for drugs against COVID-19.
Novel forms of societal behavior and political priorities during the coronavirus crisis may become permanent, creating even more favorable conditions for increased use of renewables, as discussed in a webinar hosted by the FAPESP Bioenergy Research Program.
Present in the human digestive tract, species of Candida can cause bloodstream infections in patients treated in intensive care units. An international study involving 16 hospitals found isolates with high levels of virulence.
The contagion curve in Brazil appears to have plateaued and is set to remain at the current level until at least the end of 2020. Investing in the identification and isolation of infected people and their close contacts, keeping schools closed and improving the quality of the information offered to the public are measures governments should take to make sure the situation does not become even worse.
The animal was approximately 10 cm long and lived more than 130 million years ago in what is now the state of Minas Gerais. Its morphology differs from that of all other known lizard species.
A study showed that the novel coronavirus can infect human adipocytes and that the viral load is three times higher in aged adipose cells. The results may help us understand why people with obesity and those who are older are more at risk of developing the severe form of COVID-19.
Online survey with 11,863 respondents also shows that feeling sad or depressed became routine for 39%, while overall health worsened for 26%.
Edible, biocompatible and biodegradable, these fibers have potential for various medical applications. The results are described in the journal Scientific Reports.
Researchers used statistical techniques to analyze data of 126 countries. The variables that intensified contagion at the start of the outbreak included low temperature, a large proportion of older people, foreign tourist arrivals, and greeting habits involving physical contact.
The reduction resulting from implementation of these measures in São Paulo has been calculated for the period between mid-March and early May using a mathematical model developed by a FAPESP-funded research center. The scientists also estimated that these two public health measures reduced the peak of transmission by 25% in Brasília.
Program developed by startup with FAPESP’s support was initially designed to train cognitive skills and help improve physical fitness but will now have extended functionality.
When tested in vitro, arsenic trioxide killed tumor cells and prevented the formation of new colonies. This leukemia drug also boosted the effect of radiation therapy on medulloblastoma, a type of central nervous system tumor most common in children
The compound inhibited the action of a protein activated by the virus to suppress the host’s immune response. The therapy also proved effective against dengue virus and will be tested at the University of São Paulo against coronavirus.
Testing has begun in Brazilian volunteers of two candidate vaccines at an advanced stage of development. In an online seminar co-organized by Agência FAPESP, researchers involved in Phase 3 clinical trials said the more vaccines are approved, the better mankind’s chances of controlling COVID-19.
Platform created by FAPESP in partnership with University of São Paulo, Albert Einstein Jewish Hospital, Hospital Sírio-Libanês and Fleury Group begins providing access to data for more than 177,000 patients, 5 million clinical examinations and 9,600 outcomes.
Project supported by FAPESP aims to help triage suspected COVID-19 patients.
The so-called safrinha could suffer from extreme drought events in the Center-West, Southeast and South caused by global warming, according to a study supported by FAPESP and Belmont Forum.
This is the first time Aspergillus latus has been found in a hospital. The species is more drug-resistant than its two parents and highly dangerous for patients with respiratory diseases and compromised immune systems. The researchers will now investigate the role of fungi in COVID-19.
Assembled over a five-year period by the University of São Paulo’s Medicinal Chemistry Group, the material will be tested for treating infected cells. The goal of the research is to find a compound that inhibits the key enzyme in the replication of SARS-CoV-2 without affecting human cells.
