Brazilian research group shows that valproic acid (VPA), used to treat epilepsy since the 1960s, modulates gene expression in tumor gene models and acts on DNA conformation and the histones in chromatin.
Researchers from six countries in the Americas explored bromeliad microcosms, showing how drought and flood affect the functioning of aquatic ecosystems, especially at the bottom of the food chain.
New research field promises to transform food production and treatment of diseases. A global panel of experts unified concepts to define research priorities and offer basis for legislation.
Brazilian researchers’ finding that exercising in the evening reduces blood pressure more than in the morning can help health professionals choose the time of day for aerobic training depending on the type of anti-hypertensive drug they take.
The startup’s founders were researchers at the University of São Paulo and adjusted their marketing strategy to focus on regenerative, veterinary and sports medicine thanks to training provided by PIPE, FAPESP’s program for Innovative Research in Small Business.
Researchers affiliated with institutions in Brazil and elsewhere analyzed blood work from almost 179,000 people who were tested for the novel coronavirus. They obtained the data from COVID-19 Data Sharing/BR, an open-access repository established by FAPESP.
Analysis published in Scientific Reports is based on climate models for the mid-Pliocene period, which occurred 3 million years ago and shared characteristics with present-day warming.
Economists who took part in a webinar organized by FAPESP to discuss options for the post-pandemic economic recovery said this is the right time to implement broad basic income policies.
Designed by the Human Genome and Stem Cell Research Center, the novel test may cost a quarter of those based on RT-PCR, considered the gold standard for diagnosis of the disease.
Dozens of scientists from several countries calculated upper limits to global and local temperatures if tropical forests are to survive.
Brazilian researchers use complex training program to stimulate different motor and cognitive skills simultaneously and restore brain regions associated with freezing of gait in advanced-stage patients.
Project led by researchers from Brazilian and American institutions will collect primary data during the pandemic to create a repository that will serve as a basis for future studies. The findings of the comparative analysis will be published in book form.
Integrated with the air quality management tool created by startup Omni-electronica, a collector captures viruses suspended in the environment and submits the air samples to RT-PCR testing. Monitoring of crowded locations combined with indicators created by the firm can contribute to a safer economic reopening.
Governments should assure continuity of policies that promote bioenergy, biofuels and bioproducts, say the speakers in a webinar held by the Brazilian Bioenergy Science and Technology Conference, which is supported by BIOEN-FAPESP.
Researchers isolated eight novel polyphenols from the rarest type of propolis. Two of them were found to inhibit tumor cell proliferation in laboratory assays.
The conventional process requires costly large-scale equipment. The novel method can be executed in a single step by a device no larger than a microwave oven.
Brazilian researchers observed that in uninfected adipocytes, the hormone irisin altered the expression of genes that regulate ACE-2, which encodes a protein to which the virus binds in order to invade human cells.
Researchers at the Federal University of São Carlos (UFSCar) isolated molecules present in the larvae of a blue light-emitting fungus gnat that inhabits the Appalachians. The study will help elucidate human diseases and could lead to novel biotech applications.
A literature review by researchers affiliated with universities in Brazil and the United States produces the first ever nationwide survey of land use impacts on water quality, showing how a lack of planning may affect the availability of a natural resource that is already becoming scarce.
The automated system developed by Brazilian researchers is based on an analysis of patterns of molecules in patient blood plasma.
A study conducted at the FAPESP-funded Center for Research on Inflammatory Diseases (CRID) will identify key processes triggered by SARS-CoV-2 in human cells.
In a project supported by FAPESP, researchers at São Paulo State University (UNESP) will assess the potential of peptides and other bioactive molecules to inhibit the infection of cultured cells.
In an online seminar held by FAPESP, researchers from France, the US and Brazil discussed how data repositories can be made secure and easily accessible to accelerate the development of responses to the pandemic.
Frieseomelitta varia is a docile species of economic interest as a pollinator. Its workers are sterile, and some of its genetic sequences are identical to those found in other eusocial bees, pointing to the conservation of ancestral traits.
An electrical impedance tomography system was developed by a São Paulo-based startup to monitor the lungs of patients on mechanical ventilation uninterruptedly and noninvasively.
