Researchers tested a material known as polyether siloxane, a flexible transparent hydrogel that can absorb large amounts of water without dissolving and is ideal for controlled-release drug delivery.
Scientists show that CRP3, normally produced in arteries, is expressed in saphenous vein grafts following coronary artery bypass surgery. The finding suggests that this molecule participates in adaptation to the increased blood flow and pressure resulting from arterialization.
Experiments using human brain cells and mice suggest that lithium delays cellular aging, one of the factors in neurodegenerative disorders.
Phylogenomic analysis shows that pathogen isolated in Brazilian hospital does not belong to the genus Leishmania. Researchers are investigating whether this species alone can cause severe disease or intensifies symptoms in co-infected patients.
Researchers at a Research, Innovation and Dissemination Center supported by FAPESP have created a composite with antifungal properties that are 32 times greater than those of silver by irradiating a metallic tungstate with electrons and femtosecond laser light.
Blood sugar levels in obese mice were controlled more efficiently when the mice were challenged with a glucose overload and treated with 12-HEPE, a lipid produced in response to cold by brown adipose tissue.
Compound inhibits key enzymes, interrupting the parasite’s lifecycle in human organisms and preventing transmission to vector insects. This discovery published in Science involved researchers funded by FAPESP.
Developer of a bactericidal and antimicrobial solution for the increasing of product shelf life, Nanox was supported by FAPESP through its Innovative Research in Small Business Program.
Tool developed by Brazilian researchers can be used to study disease mechanisms, plant physiology and structures of large cities, among other applications.
Color differences in the light produced by the larviform beetle are known to be caused by two enzymes with minor structural differences, but the details were hitherto unknown. This discovery has potential for applications in biotechnology.
Four substances isolated from Mimosa caesalpiniifolia were found to be more effective against thrush and candida than was fluconazole, the drug usually prescribed to treat the disease. Brazilian researchers are developing an ointment.
Using a systems biology approach, Brazilian researchers identified several genes that can be explored as therapeutic targets and as biomarkers of predisposition to chronic joint pain.
Genetic profiles of microorganisms isolated from patients with urinary tract infection display a high degree of resistance and virulence. The superbug KPC was found in samples.
A study by researchers at the Center for Cell-Based Therapy, which is supported by FAPESP, identified microRNAs involved in pluripotency maintenance and cell differentiation. The discovery paves the way to the development of drugs capable of making ESCs regress to the earliest stage of development.
The aims of these subnational institutions include bolstering the impact of Brazilian science and increasing the benefits of cross-border cooperation.
Reports launched by the Brazilian Platform on Biodiversity and Ecosystem Services estimates that forest restoration on this scale would sequester 1.39 million tons of CO2 and increase biodiversity conservation by 200% without adverse impacts on agriculture.
An article published in Nature Communications shows that three species of electric eel exist, not just one as previously described, and that one of them produces an electric shock up to 860 volts. The researchers were funded by FAPESP, the Smithsonian and National Geographic.
Brazilian startup develops a solution that assures efficient management of large truck fleets, attracting customers in agribusiness and mining.
In a study supported by FAPESP, experiments with mice showed the anti-inflammatory drug mefenamic acid to be more efficacious than praziquantel, the only drug available to combat the disease.
Brazilian researchers studied the feasibility of a space maneuver that could be used to change the course of satellites and even send spacecraft beyond the Solar System with less fuel.
Study conducted to test a procedure based on ionization of atmospheric air eliminates 99% of Candida albicans fungus that causes hospital-acquired infections, without generating toxic waste.
A titanium oxide nanofiber sheet was developed by a FAPESP-funded research group through electrospinning and atomic layer deposition.
Experiments performed in Brazil show that systematic eradication of plants contaminated by cowpea aphid-borne virus (CABMV) can keep orchards producing for at least 25 months and avoid annual replanting.
Water shortages cause economic losses for industry and agriculture, among other sectors, as well as damage human health, warns a report issued by the Brazilian Platform on Biodiversity and Ecosystem Services.
Participants at the São Paulo School of Advanced Science on Learning from Data warn that because minorities have less access to services that generate data, they tend to be underrepresented in databases used for machine learning projects.