Electrical impedance tomography system developed by startup based in São Paulo minimizes complications associated with mechanical ventilation and is used in the treatment of COVID-19 by hospitals in Italy, Spain and the US.
Scientists affiliated with the FAPESP-funded Center for Cell-Based Therapy have collected plasma from donors and are conducting a trial to check the safety and effectiveness of passive immunization.
Researchers at the University of Campinas are organizing professionals, supplies and equipment to test for COVID-19, understand how the virus works, identify existing drugs that are effective against the disease, and use 3D printing to produce parts for ventilators and personal protective equipment.
The initiative is coordinated by Butantan Institute and includes units in several cities accredited by Adolfo Lutz Institute (IAL), the regional reference laboratory. Short supply is the main bottleneck delaying the expansion of testing in the state.
Based in São Paulo, Magnamed will produce 6,500 ventilators by August for use in treating COVID-19 patients, working in partnership with a pool of leading Brazilian and multinational corporations.
Diagnostic strategy developed by Brazilian researchers can also be used to distinguish MS from neuromyelitis optica, another demyelinating disorder. The two diseases have similar symptoms but must be treated differently.
The review article by researchers at the University of São Paulo shows the advantages of this technological alternative, which is nontoxic and much cheaper than other methods.
One of the studies will evaluate the effectiveness of drugs that inhibit bradykinin against pulmonary inflammation in critical patients. The other will analyze the transmission dynamics of the novel coronavirus in a small town in Amazonia.
Brazilian researchers use minimally invasive technique to perform autopsies on deceased patients diagnosed with COVID-19, with the aim of assisting physicians and other health workers.
Research by the FAPESP-funded Center for Metropolitan Studies (CEM) shows that it is not feasible to separate high-risk groups in low-income communities, where the majority of the Brazilian population live. The problem is especially acute in the Southeast region, with metropolitan São Paulo displaying the largest deficit.
Metabolic changes associated with diseases such as pulmonary hypertension and chronic obstructive pulmonary disease may reprogram gene expression to increase production of a protein used by SARS-CoV-2 to penetrate lung cells.
Groundbreaking study shows that regular exercise in prepubertal childhood improves the functioning of cells essential to vascular health. Babies weighing less than 2.5 kg at birth are more likely to develop cardiovascular diseases in adulthood.
Species never before found in humans described in PLOS ONE belong to the genera Ambidensovirus and Chapparvovirus. Researchers do not yet know if they can cause disease.
Scientists at Brazil’s National Energy and Materials Research Center are analyzing the antiviral action of commercially available drugs in cultured cells.
Researchers explains how their experience with the Zika virus, made possible with funding from FAPESP, helped them to cultured the SARS-CoV-2 coronavirus.
Scientists in the state of São Paulo are working on a method of diagnosing the disease quickly and cheaply by combining an analysis of the pattern of molecules in body fluids with machine learning.
Tool developed by a firm supported by FAPESP is being used to assess student learning in primary and secondary schools in the state of São Paulo.
Research and higher-education institutes from the state of São Paulo have signed an agreement with the Oak Ridge National Laboratory, an institution associated with United States Energy Department with great experience in managing atmospheric data; the initiative’s goal is to make knowledge generated with public funding accessible.
A population study conducted at a regional center of the state of São Paulo (Brazil) showed that 32.9% of subjects under 40 had no immunity against the disease, compared with only 1% in those over 50.
At an event organized by FAPESP and the UK’s Royal Society, researchers showed how partnerships are important in producing scientific results at the knowledge frontier.
The imaging analysis system available at the University of São Paulo enhances the effectiveness of biological control of South American fruit flies based on the sterilization of males. The species mainly damages apple and peach orchards in the South Region of Brazil.
Brazilian researchers show that if 25% of a one-hectare forest remnant is cut down, the impact on the local climate will be a temperature increase of 1 °C. The study is published in PLOS ONE.
The blood test method makes use of machine learning and can be used to predict whether patients will put on weight, unless they change their habits. The project was conducted in Brazil with funding from FAPESP.
Experiments with rats indicate that brain cells submitted to several forms of hypoxia underwent alterations to their energy production mechanism. Such condition may affect the fetus in pregnant women who have developed pre-eclampsia, a high blood pressure disorder.
A discovery by scientists affiliated with a research center supported by FAPESP could contribute to the development of more powerful photosensitizers. When these molecules are exposed to light, they trigger biochemical processes that lead to the disruption of the cell membranes of tumors or pathogens.
