A study conducted at a FAPESP-supported research center discovered a link between the protein VAPB and tumor cell proliferation in medulloblastoma, one of the most common and aggressive brain tumors in children.
With the new contributions from abroad, the Scientific Expeditions call, issued in partnership with the National Council for Scientific and Technological Development, now has a fund totaling some BRL 94 million.
The analysis compared the effects of artepillin C on healthy cells and cancer cells, as well as the effects on its efficacy of variations in the medium’s pH.
The startup has been supported by FAPESP since its foundation in 2020. The device can be used to make film for perovskite solar cells, biomaterials for wound dressings and tissue regeneration, and novel drug and cosmetic delivery systems.
CD4+ T cells play an important role in the immune response to pulmonary infections, but excessive amounts can damage the lungs. In experiments with mice, researchers at the University of São Paulo discovered what leads to this exacerbated response.
Data from the Phase 3 clinical trial was published on February 1st in The New England Journal of Medicine. The vaccine is safe for both participants who have had dengue and those who have never been exposed to the virus before.
The aim is to foster scientific and technological collaboration between researchers affiliated with the Chinese entity and colleagues at universities and research institutions in São Paulo state.
André Morandini, Director of the University of São Paulo’s Center for Marine Biology, was on the team that has published a description of a rare medusa found at a depth of 812 meters. The animal has been sighted only twice in a deep-sea volcanic structure called Sumisu Caldera, in the Ogasawara Islands.
The study, which was conducted by Brazilian researchers, supports sustainable agriculture and offers contributions to public policy formulation.
This part of the seafloor in the South Atlantic is rich in cobalt, nickel and lithium, as well as tellurium and other rare earths critical to the energy transition. The scientists plan to continue research on its natural processes as a contribution to prospecting efforts.
Developed by a team of Brazilian researchers, the device is made of plant-based material with little environmental impact, and detects pesticides in a few minutes, helping to certify food safety.
In 18 cities of the Barretos region, where the proportion of Black people in the population is smaller, cancer kills more members of this ethnic group, whereas in the capital of the same state, it kills more White people, according to a study that compares cancer mortality rates and points to ways of reducing inequalities in diagnosis and treatment.
The platform, developed by a company based in São Carlos (São Paulo state, Brazil) and supported by FAPESP, is able to predict and permit correction of failures in order to avoid unplanned factory production line downtime.
The material is a compound similar to clay and enables inspectors to carry out in-situ assessment of structural conditions in buildings, bridges, dams and other structures without having to drill for samples and analyze them in a laboratory.
The two parties are interested in collaborative research on sustainable use of biodiversity in the Amazon, prevention of transmissible and chronic diseases, and sustainable construction, among other subjects.
In experiments with rats, researchers at the University of São Paulo analyzed brain tissue and detected alterations in genes associated with energy metabolism.
In experiments with rats, researchers at São Paulo State University detected changes in the expression of more than 700 genes in offspring. One of these genes is known to be associated with prostate cancer.
The solution, which was developed via a project supported by FAPESP, aims to help farmers assess risks and forecast future prices.
Some species of cetacean are up to 4 meters in length, while others reach 30 meters. According to researchers at the State University of Campinas, genes that favor the colossal growth of these mammals also inhibit the development of cancer.
The study analyzed data for 13 Atlantic Rainforest restoration areas involving ten species of native trees that could be commercially useful to the timber industry. Publication of the findings comes during the UN Decade on Ecosystem Restoration.
Indonesia, Malaysia, Philippines, Singapore Thailand and Vietnam have dynamic economies and similarities with Brazil that make collaboration particularly relevant.
The purpose of the event was to build ties and foster collaboration between researchers in São Paulo state and the United Kingdom.
The land crab Johngarthia lagostoma occurs only on four ocean islands, three of which are in Brazil, but little is known of its natural history. Brazilian researchers discovered that a hill and beach on Trindade Island play a key role in the species’ reproductive cycle and survival.
Researchers at the University of São Paulo and São Paulo state’s Center for Epidemiological Surveillance observed spatial and temporal patterns of occurrence and co-occurrence for the two arboviral diseases in all Brazilian municipalities, alongside the influence of environmental and socio-economic factors.
A study published in the journal Science shows for the first time the degree of threat to all tree species in the biome, classifying 65% as vulnerable or endangered to some extent. According to the authors, their findings are conservative – the actual situation could be even more alarming.
