In animal tests conducted at São Paulo State University (UNESP), the strategy reduced spleen and liver parasite numbers by 99.9%.
Researchers at the University of São Paulo analyzed data from 115 children who suffered from conditions considered syndromic (with several associated symptoms) and found a high incidence of overlapping genetic alterations. They argue that identification of genetic mutations can make diagnosis and treatment more accurate.
The opossum was found dead in a park in the center of Campinas, a large city in São Paulo state (Brazil), with the same viral variant as fruit-eating bats. These mammals are regularly detected in cities, where they are often attacked by dogs, so they can be considered sentinel species for infectious disease surveillance.
Through experiments in roundworms of the species C. elegans, scientists at a FAPESP-supported research center showed that lifespan is reduced when RNA transfer between cells in different tissues is dysregulated.
A study conducted in a poor suburb of São Paulo city (Brazil) analyzed how low-income communities deal with the hardships deriving from the economic crisis that began in 2014 and worsened during the pandemic.
Blood pressure rose in offspring born to high-fructose rats, and physiological regulation of their cardiovascular system was impaired. High-fructose syrup is widely used as a sweetener by the food and beverage industry.
Considered an invasive species, Sus scrofa causes damage to farmers in an important part of Brazil’s savanna-like biome. The researchers analyzed 55 landscapes in São Paulo state, observing larger numbers of native mammals in areas with well-conserved vegetation and diversified crops, while native species richness was far lower in areas of monoculture.
A study led by Brazilian researchers suggests that the mechanism that exacerbates dengue infection following a case of zika differs from that acting on second-time dengue patients. The finding is relevant to the development of a zika vaccine.
A study conducted at a FAPESP-supported research center discovered a link between the protein VAPB and tumor cell proliferation in medulloblastoma, one of the most common and aggressive brain tumors in children.
With the new contributions from abroad, the Scientific Expeditions call, issued in partnership with the National Council for Scientific and Technological Development, now has a fund totaling some BRL 94 million.
The analysis compared the effects of artepillin C on healthy cells and cancer cells, as well as the effects on its efficacy of variations in the medium’s pH.
The startup has been supported by FAPESP since its foundation in 2020. The device can be used to make film for perovskite solar cells, biomaterials for wound dressings and tissue regeneration, and novel drug and cosmetic delivery systems.
CD4+ T cells play an important role in the immune response to pulmonary infections, but excessive amounts can damage the lungs. In experiments with mice, researchers at the University of São Paulo discovered what leads to this exacerbated response.
Data from the Phase 3 clinical trial was published on February 1st in The New England Journal of Medicine. The vaccine is safe for both participants who have had dengue and those who have never been exposed to the virus before.
The aim is to foster scientific and technological collaboration between researchers affiliated with the Chinese entity and colleagues at universities and research institutions in São Paulo state.
André Morandini, Director of the University of São Paulo’s Center for Marine Biology, was on the team that has published a description of a rare medusa found at a depth of 812 meters. The animal has been sighted only twice in a deep-sea volcanic structure called Sumisu Caldera, in the Ogasawara Islands.
The study, which was conducted by Brazilian researchers, supports sustainable agriculture and offers contributions to public policy formulation.
This part of the seafloor in the South Atlantic is rich in cobalt, nickel and lithium, as well as tellurium and other rare earths critical to the energy transition. The scientists plan to continue research on its natural processes as a contribution to prospecting efforts.
Developed by a team of Brazilian researchers, the device is made of plant-based material with little environmental impact, and detects pesticides in a few minutes, helping to certify food safety.
In 18 cities of the Barretos region, where the proportion of Black people in the population is smaller, cancer kills more members of this ethnic group, whereas in the capital of the same state, it kills more White people, according to a study that compares cancer mortality rates and points to ways of reducing inequalities in diagnosis and treatment.
The platform, developed by a company based in São Carlos (São Paulo state, Brazil) and supported by FAPESP, is able to predict and permit correction of failures in order to avoid unplanned factory production line downtime.
The material is a compound similar to clay and enables inspectors to carry out in-situ assessment of structural conditions in buildings, bridges, dams and other structures without having to drill for samples and analyze them in a laboratory.
The two parties are interested in collaborative research on sustainable use of biodiversity in the Amazon, prevention of transmissible and chronic diseases, and sustainable construction, among other subjects.
In experiments with rats, researchers at the University of São Paulo analyzed brain tissue and detected alterations in genes associated with energy metabolism.
In experiments with rats, researchers at São Paulo State University detected changes in the expression of more than 700 genes in offspring. One of these genes is known to be associated with prostate cancer.
