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FAPESP and the Sustainable Development Goals

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SDG 3 Good Health and Well-being

News

SDG 3 Good Health and Well-being

Combination of omega-3 and aspirin helps treat periodontitis in diabetics
SDG 3
Combination of omega-3 and aspirin helps treat periodontitis in diabetics

Study conducted at São Paulo State University demonstrates for first time that simple and inexpensive strategy yields better results than conventional treatment and avoids indiscriminate use of antibiotics.


Study could lead to diagnostic test for schizophrenia and bipolarity
SDG 3
Study could lead to diagnostic test for schizophrenia and bipolarity

Methodology developed by Brazilian researchers is based on analysis of metabolites in blood serum. Innovation has been patented and reported in Journal of Psychiatric Research.


Immunity induced by other coronaviruses may not protect older people against COVID-19
SDG 3
Immunity induced by other coronaviruses may not protect older people against COVID-19

Study led by researchers at Oxford University suggests that after successive infections by the coronaviruses that cause common colds throughout life the defense system becomes specialized and cannot recognize emergent varieties such as SARS-CoV-2.


Obesity implies high risk of severe COVID-19 regardless of age, sex, ethnicity and pre-existing diseases
SDG 3
Obesity implies high risk of severe COVID-19 regardless of age, sex, ethnicity and pre-existing diseases

Conclusion presented by Brazilian researchers in Obesity Research & Clinical Practice is based on analysis of nine clinical studies involving 6,577 patients infected by SARS-CoV-2 in five countries.


Study describes COVID-19 transmission pattern
SDG 3
Study describes COVID-19 transmission pattern

Model developed by Brazilian researchers predicts spatial and temporal evolution of epidemic diseases and can help plan more effective social isolation programs with less socio-economic impact.


Community health workers could play a key part in combating the pandemic in Brazil, researcher says
SDG 1, SDG 3
Community health workers could play a key part in combating the pandemic in Brazil, researcher says

An article in The Lancet stresses the vulnerability of these health workers, whose readiness to counter fake news with trustworthy information, and to monitor COVID-19 patients in home isolation, has been neglected.


An inexpensive technique to display 3D images of novel coronavirus in cells
SDG 3, SDG 9
An inexpensive technique to display 3D images of novel coronavirus in cells

Protocol developed by Brazilian researchers shows SARS-CoV-2 replicating near cell nucleus. Methodology helps scientists understand coronavirus’s action mechanism and could also be used to study other viruses.


Nationwide epidemiological survey points to decelerating transmission of COVID-19 in most of Brazil
SDG 3
Nationwide epidemiological survey points to decelerating transmission of COVID-19 in most of Brazil

In the fourth phase of EPICOVID-19 BR, the proportion of the population with antibodies against the novel coronavirus fell from 3.8% in June to 1.4% in August in 133 cities. According to the authors, the methodology accurately estimates contagion rates in the previous 45 days.


Anti-convulsant drug can modify DNA conformation and interact with chromosome proteins
SDG 3
Anti-convulsant drug can modify DNA conformation and interact with chromosome proteins

Brazilian research group shows that valproic acid (VPA), used to treat epilepsy since the 1960s, modulates gene expression in tumor gene models and acts on DNA conformation and the histones in chromatin.


A study could provide guidelines for exercise training aimed at high blood pressure patients
SDG 3
A study could provide guidelines for exercise training aimed at high blood pressure patients

Brazilian researchers’ finding that exercising in the evening reduces blood pressure more than in the morning can help health professionals choose the time of day for aerobic training depending on the type of anti-hypertensive drug they take.


Study shows influence of biological sex and age on clinical profile of COVID-19 in Brazil
SDG 3
Study shows influence of biological sex and age on clinical profile of COVID-19 in Brazil

Researchers affiliated with institutions in Brazil and elsewhere analyzed blood work from almost 179,000 people who were tested for the novel coronavirus. They obtained the data from COVID-19 Data Sharing/BR, an open-access repository established by FAPESP.


Brazilian researchers develop saliva-based COVID-19 diagnostic test
SDG 3, SDG 9
Brazilian researchers develop saliva-based COVID-19 diagnostic test

Designed by the Human Genome and Stem Cell Research Center, the novel test may cost a quarter of those based on RT-PCR, considered the gold standard for diagnosis of the disease.


Exercise protocol mitigates one of the most incapacitating symptoms of Parkinson’s disease
SDG 3
Exercise protocol mitigates one of the most incapacitating symptoms of Parkinson’s disease

Brazilian researchers use complex training program to stimulate different motor and cognitive skills simultaneously and restore brain regions associated with freezing of gait in advanced-stage patients.


International study will compare different countries’ responses to COVID-19
SDG 3, SDG 16
International study will compare different countries’ responses to COVID-19

Project led by researchers from Brazilian and American institutions will collect primary data during the pandemic to create a repository that will serve as a basis for future studies. The findings of the comparative analysis will be published in book form.


System monitors presence of novel coronavirus in air
SDG 3, SDG 9, SDG 12
System monitors presence of novel coronavirus in air

Integrated with the air quality management tool created by startup Omni-electronica, a collector captures viruses suspended in the environment and submits the air samples to RT-PCR testing. Monitoring of crowded locations combined with indicators created by the firm can contribute to a safer economic reopening.


Substances with anti-cancer action are identified in Brazilian red propolis
SDG 3
Substances with anti-cancer action are identified in Brazilian red propolis

Researchers isolated eight novel polyphenols from the rarest type of propolis. Two of them were found to inhibit tumor cell proliferation in laboratory assays.


Exercise hormone may modulate genes associated with replication of novel coronavirus, study suggests
SDG 3
Exercise hormone may modulate genes associated with replication of novel coronavirus, study suggests

Brazilian researchers observed that in uninfected adipocytes, the hormone irisin altered the expression of genes that regulate ACE-2, which encodes a protein to which the virus binds in order to invade human cells.


Technique uses artificial intelligence to diagnose COVID-19 and predict risk of complications
SDG 3, SDG 9
Technique uses artificial intelligence to diagnose COVID-19 and predict risk of complications

The automated system developed by Brazilian researchers is based on an analysis of patterns of molecules in patient blood plasma.


Researchers prepare to screen genes associated with the replication of novel coronavirus
SDG 3
Researchers prepare to screen genes associated with the replication of novel coronavirus

A study conducted at the FAPESP-funded Center for Research on Inflammatory Diseases (CRID) will identify key processes triggered by SARS-CoV-2 in human cells.


Action of 50 synthetic compounds will be tested against novel coronavirus
SDG 3
Action of 50 synthetic compounds will be tested against novel coronavirus

In a project supported by FAPESP, researchers at São Paulo State University (UNESP) will assess the potential of peptides and other bioactive molecules to inhibit the infection of cultured cells.


Brazilian technology is used in several countries to treat COVID-19 patients
SDG 3, SDG 9
Brazilian technology is used in several countries to treat COVID-19 patients

An electrical impedance tomography system was developed by a São Paulo-based startup to monitor the lungs of patients on mechanical ventilation uninterruptedly and noninvasively.


Colchicine, an anti-inflammatory drug, accelerates recovery of hospitalized COVID-19 patients
SDG 3
Colchicine, an anti-inflammatory drug, accelerates recovery of hospitalized COVID-19 patients

Benefits were observed in a clinical trial involving 38 volunteers treated at the teaching hospital of the University of São Paulo’s Ribeirão Preto Medical School. The drug is cheap and can shorten ICU stays but should not be used outside hospitals, the researchers warn.


Researchers investigate genetic factors behind resistance or susceptibility to COVID-19
SDG 3
Researchers investigate genetic factors behind resistance or susceptibility to COVID-19

A study is being conducted by a research center supported by FAPESP to determine whether people who develop severe forms of the disease have risk genes and whether asymptomatic people or patients with only mild symptoms have protective genes.


COVID-19 numbers for Amazonas reinforce the theory that herd immunity may be reached sooner than expected
SDG 3
COVID-19 numbers for Amazonas reinforce the theory that herd immunity may be reached sooner than expected

Specialists discussed the situation in a webinar held by Agência FAPESP and Canal Butantan. However, they stressed that achieving herd immunity should not be public policy, as clearly shown by the tragic death toll suffered in Manaus, the state capital of Amazonas.


Novel, rapid tests to detect dengue, Zika, yellow fever and other viruses are validated
SDG 3
Novel, rapid tests to detect dengue, Zika, yellow fever and other viruses are validated

The method identifies and distinguishes between flaviviruses that cause many diseases in humans and animals in Brazil.


News about research projects funded by FAPESP and articulated with the SDGs: