Study involving more than 200 hospitalized patients in São Paulo shows physically active individuals are not fully protected against the disease.
Clinical trial conducted in Brazil suggests the treatment can be beneficial if administered within ten days of symptom onset.
Brazilian researchers used functional magnetic resonance imaging to assess 86 volunteers who had moderate COVID-19 and compared the results with those of uninfected volunteers. Preliminary findings have not yet been published but were presented during a conference held at the University of Campinas.
More than 1,000 volunteers completed an online questionnaire designed by Brazilian researchers. The results show that more women are cooking, sitting down to eat, snacking between meals, and ordering takeaway meals, while dieting and supermarket shopping have declined.
Researchers at a center for neuromathematics say dreams reflect the fear and anxiety fueled by the disease.
Technology based on nanoparticles identifies IgG antibodies and costs only about a fifth of similar devices now on the market. It was developed by scientists at the University of São Paulo and Brazilian startup Biolinker.
Brazilian researchers applied an examination protocol based on an analysis of 12 lung regions to 180 severe patients and found that the higher the lung ultrasound score the greater the risk of ICU admission, intubation and death.
A study by researchers at the University of São Paulo showed that the blood serum of severe patients contained high levels of the neurotransmitter acetylcholine and lipid mediators derived from arachidonic acid. The discovery may help improve the prognosis of such patients and the treatment available to them.
According to a study published in Frontiers in Immunology, the reason is their genetic heterogeneity and lack of proportional representation in the Brazilian bone marrow bank.
Based on a reaction between yeast and the novel coronavirus, the test will rapidly detect the presence of SARS-CoV-2 in saliva and will be available by mid-2021.
Researchers at York University in Canada and the University of Campinas in Brazil used mathematical modeling to estimate the short-term impact of vaccination. Abandoning non-pharmaceutical interventions too soon could cancel out the benefit, they warn.
The hormone acts as a barrier against SARS-CoV-2, blocking the expression of genes that encode proteins in cells serving as viral entry points, according to a study by researchers at the University of São Paulo.
The phenomenon may be associated with a deficiency of the protein mitofusin-2 in the mother’s eggs, which affects the shape and functioning of mitochondria. The finding was based on experiments with mice conducted at the Federal University of São Carlos and reported in the journal Molecular Human Reproduction.
In an article published in Nature Communications, Brazilian researchers show for the first time that in severe cases of scorpion envenomation it is the neuroimmune reaction triggered by the venom that leads to death.
Researchers at the University of São Paulo found that the SARS-CoV-2 variant’s spike protein interacted more strongly with the ACE2 receptor used by the virus to invade and replicate in human cells.
In a review article published in Frontiers of Endocrinology, Brazilian researchers estimate a reduction of 35% in levels of physical activity and a rise of 28% in sedentary behavior in the initial months of confinement imposed by the pandemic.
Experts tell Agência FAPESP about factors that may be associated with the rapid rise in daily case numbers in the capital of Amazonas State, where a six-month state of emergency has been declared.
When researchers reanalyzed datasets from more than 1,000 patients, they found differences between men and women in the expression of genes associated with the functioning of immune cells and the production of inflammatory molecules. The findings point to possible targets for treatment of both sexes.
After 14 years studying the action of the enzyme LMWPTP in tumor cells, Brazilian researchers conclude that the molecule is associated with chemotherapy resistance and metastasis.
Discovery by Brazilian scientists paves the way for the study of more potent molecules capable of directly destroying parasites underlying elephantiasis and cutaneous leishmaniasis, with fewer adverse side-effects.
Technology to manage hospital flows is being tested by health units in metropolitan São Paulo.
The Brazilian research group used epigenetic modulators to try to “erase” the damage done by stress to neuroplasticity. The study showed that acute intervention in epigenetic mechanisms produces antidepressant-like effects more rapidly than conventional drugs.
The raw materials and inputs for vaccines are produced in different countries and subject to undersupply risk, said speakers in a webinar on Facing the Challenges of Vaccine Distribution organized by FAPESP.
Brazilian researchers tested the antichagasic properties of VmCT1, obtained from the venom of Vaejovis mexicanus, a scorpion harmless to humans, and synthesized novel analogs to redesign the native molecule.
The online survey was conducted in Brazil and completed by 938 survivors of the disease whose diagnosis was confirmed by RT-PCR or serological test. Those who regularly had at least 150 minutes per week of moderately intense aerobic exercise or 75 minutes of high-intensity training were considered sufficiently active, in accordance with the WHO’s recommendations.
