Researchers used C. elegans as an animal model to investigate the importance of certain human genes for the treatment of schizophrenia.
Experiments with mice suggest that treatment with atorvastatin can attenuate adipose tissue remodeling, leading to rapid weight loss and muscle atrophy.
Researchers affiliated with the Structural Genomics Consortium in Brazil control a cellular communication pathway using chemical compounds that inhibit the kinase AAK1.
A scientific study using mice shows that cognitive and physical stimulation reduces senile plaque deposition and improves spatial memory.
Canadian and Brazilian researchers describe the use of 13 molecular tools for measuring different intracellular signaling pathways and evaluating the action mechanisms of new drugs.
A study published in Scientific Reports identifies changes to neutrophils that appear to explain why people suffering from obesity and type 2 diabetes are more likely to contract infectious diseases.
The hormone that tells an organism when it is dark and prepares us for sleep also regulates the supply of stem cells in the bone marrow, according to a study involving Brazilian researchers.
Performed under the aegis of the Center for Cell-Based Therapy (CTC), the study is the first to investigate mitochondrial DNA in search of alterations associated with penile tumors.
System developed by Hoobox interprets facial expressions and other behavioral cues and can be used to assess the status of patients in intensive care, babies in cribs or passengers in self-driving cars.
Biomaterial kept mesenchymal stem cells alive and considerably reduced the size of the lesion caused by stroke in a study involving mice. The procedure could help repair brain areas in even larger lesions.
This innovation has been developed by researchers based in Brazil and the US. It not only halts the progression of the heart failure but also improves the heart’s capacity to pump blood.
Project presented at FAPESP Week London identifies genes that allow bacteria to survive in the digestive tract of poultry and thus infect humans.
The study of natural toxins and their derivatives may help in the development of medicines to treat diseases like cancer and osteoarthritis, says coordinator of the Center of Excellence in New Target Discovery.
Scientists from the University of Birmingham and the School of Medical Sciences at the Santa Casa de São Paulo are using cell reprogramming techniques to grasp at how Wolfram and Niemann-Pick syndromes act on the brain.
Glaucius Oliva speaks at FAPESP Week London about the line of work of the Center for Research and Innovation in Biodiversity and Drug Discovery and how the UK collaboration helps developing structural biology in Brazil.
Animal experiments have shown that caloric restriction causes cellular changes that can prevent diseases, the subject of a session at FAPESP Week London.
Gene-edited pigs may reduce Brazil’s transplant waiting list. Still in its initial stages and presented at FAPESP Week London, a project will assess how patients awaiting kidney transplants react to porcine blood.
Description of the mechanism could enhance the efficiency of photodynamic therapy, a medical treatment for cancer and bacterial infection, and permit the development of more efficient sunscreens.
A study conducted in Brazil, China, Finland, Ghana, India and the United States found 94% of meals served in restaurants contain more than the recommended number of calories according to the UK’s National Health Service.
Physically active men who are not overweight but who have a relatively high waist-stature ratio are more likely to develop heart disorders, according to a study by Brazilian researchers.
Research shows that rapid urbanization in São Paulo City, Brazil, is influencing wing morphology in the mosquitoes that transmit dengue and malaria.
After taking beta-alanine for 28 days, volunteers eliminated more toxic substances from skeletal muscle following physical exercise. This discovery could help treat diseases caused by oxidative stress.
A study conducted in Brazil showed protective effects of flavonoid rutin against bleeding and inflammation due to snakebite.
The compound called GA-Hecate also acts on bacteria, fungi and cancer cells and will be tested against Zika and yellow fever viruses.
