A review article authored by Brazilian researchers evaluated several compounds with therapeutic potential against gastric tumors.
Novel therapy developed in Israel uses a laser-activated photosensitizing drug to attack early-stage prostate cancer, according to a presentation delivered to an international event on biophotonics supported by FAPESP.
Survey covering 163 municipalities showed that toothache, bleeding and periodontal disease affected 50.57% of respondents, a proportion considered high by specialists.
Present in the most aggressive cases of a disease known as SPTCL and accounting for 60% of all cases, these mutations make the immune system attack the organism instead of protecting it.
A long noncoding RNA protects cancer cells and increases their proliferation. The discovery could lead to treatment for drug-resistant types of melanoma.
Method developed by scientists in Brazil and Canada can prevent transmission of diseases to organ recipients.
A Brazilian study shows that, like leptin, growth hormone contributes directly to energy conservation when the body loses weight.
A project conducted by researchers in Brazil and the US investigated bacteria living in symbiosis with insects as a source for novel drugs.
By identifying signature of 16 disease-related microbial species, this international study with Brazilian participation may contribute to develop predictive tests valid for populations with different dietary cultures.
Brazilian and British scientists are testing a software tool that could lower the cost of providing care to elderly patients with depression.
Few novel drugs have been developed to treat neglected diseases in recent decades, Brazilian researchers warn.
Researchers used C. elegans as an animal model to investigate the importance of certain human genes for the treatment of schizophrenia.
Experiments with mice suggest that treatment with atorvastatin can attenuate adipose tissue remodeling, leading to rapid weight loss and muscle atrophy.
Researchers affiliated with the Structural Genomics Consortium in Brazil control a cellular communication pathway using chemical compounds that inhibit the kinase AAK1.
A scientific study using mice shows that cognitive and physical stimulation reduces senile plaque deposition and improves spatial memory.
Canadian and Brazilian researchers describe the use of 13 molecular tools for measuring different intracellular signaling pathways and evaluating the action mechanisms of new drugs.
A study published in Scientific Reports identifies changes to neutrophils that appear to explain why people suffering from obesity and type 2 diabetes are more likely to contract infectious diseases.
The hormone that tells an organism when it is dark and prepares us for sleep also regulates the supply of stem cells in the bone marrow, according to a study involving Brazilian researchers.
Performed under the aegis of the Center for Cell-Based Therapy (CTC), the study is the first to investigate mitochondrial DNA in search of alterations associated with penile tumors.
System developed by Hoobox interprets facial expressions and other behavioral cues and can be used to assess the status of patients in intensive care, babies in cribs or passengers in self-driving cars.
Biomaterial kept mesenchymal stem cells alive and considerably reduced the size of the lesion caused by stroke in a study involving mice. The procedure could help repair brain areas in even larger lesions.
This innovation has been developed by researchers based in Brazil and the US. It not only halts the progression of the heart failure but also improves the heart’s capacity to pump blood.
Project presented at FAPESP Week London identifies genes that allow bacteria to survive in the digestive tract of poultry and thus infect humans.
The study of natural toxins and their derivatives may help in the development of medicines to treat diseases like cancer and osteoarthritis, says coordinator of the Center of Excellence in New Target Discovery.
Scientists from the University of Birmingham and the School of Medical Sciences at the Santa Casa de São Paulo are using cell reprogramming techniques to grasp at how Wolfram and Niemann-Pick syndromes act on the brain.