Fapesp

FAPESP and the Sustainable Development Goals

News

SDG 3 Good Health and Well-being

News

SDG 3 Good Health and Well-being

Study highlights anti-tumor activity of curcumin on stomach cancer
SDG 3
Study highlights anti-tumor activity of curcumin on stomach cancer

A review article authored by Brazilian researchers evaluated several compounds with therapeutic potential against gastric tumors.


Pigment produced by aquatic bacteria combats prostate cancer
SDG 3
Pigment produced by aquatic bacteria combats prostate cancer

Novel therapy developed in Israel uses a laser-activated photosensitizing drug to attack early-stage prostate cancer, according to a presentation delivered to an international event on biophotonics supported by FAPESP.


Oral health problems affect half of adults aged 35-44 surveyed in São Paulo State
SDG 3
Oral health problems affect half of adults aged 35-44 surveyed in São Paulo State

Survey covering 163 municipalities showed that toothache, bleeding and periodontal disease affected 50.57% of respondents, a proportion considered high by specialists.


Mutations responsible for rare type of lymphoma have been discovered
SDG 3
Mutations responsible for rare type of lymphoma have been discovered

Present in the most aggressive cases of a disease known as SPTCL and accounting for 60% of all cases, these mutations make the immune system attack the organism instead of protecting it.


Study identifies new functions of molecule involved in melanoma
SDG 3
Study identifies new functions of molecule involved in melanoma

A long noncoding RNA protects cancer cells and increases their proliferation. The discovery could lead to treatment for drug-resistant types of melanoma.


Biophotonic therapy eliminates bacteria and viruses from organs before transplantation
SDG 3
Biophotonic therapy eliminates bacteria and viruses from organs before transplantation

Method developed by scientists in Brazil and Canada can prevent transmission of diseases to organ recipients.


Growth hormone acts to prevent weight loss
SDG 3
Growth hormone acts to prevent weight loss

A Brazilian study shows that, like leptin, growth hormone contributes directly to energy conservation when the body loses weight.


Compound that kills drug-resistant fungi is isolated from ant microbiota
SDG 3
Compound that kills drug-resistant fungi is isolated from ant microbiota

A project conducted by researchers in Brazil and the US investigated bacteria living in symbiosis with insects as a source for novel drugs.


Intestinal bacteria can be used to predict occurrence of colorectal cancer
SDG 3
Intestinal bacteria can be used to predict occurrence of colorectal cancer

By identifying signature of 16 disease-related microbial species, this international study with Brazilian participation may contribute to develop predictive tests valid for populations with different dietary cultures.


Computer app helps treat depression in older adults
SDG 3, SDG 9
Computer app helps treat depression in older adults

Brazilian and British scientists are testing a software tool that could lower the cost of providing care to elderly patients with depression.


Neglected diseases continue to require attention despite progress
SDG 3
Neglected diseases continue to require attention despite progress

Few novel drugs have been developed to treat neglected diseases in recent decades, Brazilian researchers warn.


Experiments with roundworms suggest alternatives for the treatment of schizophrenia
SDG 3
Experiments with roundworms suggest alternatives for the treatment of schizophrenia

Researchers used C. elegans as an animal model to investigate the importance of certain human genes for the treatment of schizophrenia.


Drug used to control cholesterol found effective against cancer-associated cachexia
SDG 3
Drug used to control cholesterol found effective against cancer-associated cachexia

Experiments with mice suggest that treatment with atorvastatin can attenuate adipose tissue remodeling, leading to rapid weight loss and muscle atrophy.


Chemical probe can help regulate an essential signaling pathway in cells
SDG 3
Chemical probe can help regulate an essential signaling pathway in cells

Researchers affiliated with the Structural Genomics Consortium in Brazil control a cellular communication pathway using chemical compounds that inhibit the kinase AAK1.


Physical and social activities protect the brain against Alzheimer’s disease
SDG 3
Physical and social activities protect the brain against Alzheimer’s disease

A scientific study using mice shows that cognitive and physical stimulation reduces senile plaque deposition and improves spatial memory.


Biosensors make new approaches to drug discovery possible
SDG 3
Biosensors make new approaches to drug discovery possible

Canadian and Brazilian researchers describe the use of 13 molecular tools for measuring different intracellular signaling pathways and evaluating the action mechanisms of new drugs.


Cellular alterations increase the vulnerability of obese and diabetic individuals to infections
SDG 3
Cellular alterations increase the vulnerability of obese and diabetic individuals to infections

A study published in Scientific Reports identifies changes to neutrophils that appear to explain why people suffering from obesity and type 2 diabetes are more likely to contract infectious diseases.


Melatonin may help boost the success of bone marrow transplants
SDG 3
Melatonin may help boost the success of bone marrow transplants

The hormone that tells an organism when it is dark and prepares us for sleep also regulates the supply of stem cells in the bone marrow, according to a study involving Brazilian researchers.


Study reveals a link between penile cancer and mitochondrial genome mutations
SDG 3
Study reveals a link between penile cancer and mitochondrial genome mutations

Performed under the aegis of the Center for Cell-Based Therapy (CTC), the study is the first to investigate mitochondrial DNA in search of alterations associated with penile tumors.


Startup uses facial recognition technology to monitor human behavior
SDG 3, SDG 9
Startup uses facial recognition technology to monitor human behavior

System developed by Hoobox interprets facial expressions and other behavioral cues and can be used to assess the status of patients in intensive care, babies in cribs or passengers in self-driving cars.


Stem cells help repair brain injury due to stroke
SDG 3
Stem cells help repair brain injury due to stroke

Biomaterial kept mesenchymal stem cells alive and considerably reduced the size of the lesion caused by stroke in a study involving mice. The procedure could help repair brain areas in even larger lesions.


Researchers create a new molecule to treat heart failure
SDG 3
Researchers create a new molecule to treat heart failure

This innovation has been developed by researchers based in Brazil and the US. It not only halts the progression of the heart failure but also improves the heart’s capacity to pump blood.


Genetic study seeks to prevent foodborne infection caused by <i>Salmonella</i>
SDG 3
Genetic study seeks to prevent foodborne infection caused by <i>Salmonella</i>

Project presented at FAPESP Week London identifies genes that allow bacteria to survive in the digestive tract of poultry and thus infect humans.


Venoms are sources in the search for new medicines
SDG 3, SDG 9
Venoms are sources in the search for new medicines

The study of natural toxins and their derivatives may help in the development of medicines to treat diseases like cancer and osteoarthritis, says coordinator of the Center of Excellence in New Target Discovery.


Study investigates the underlying mechanisms of neurodegenerative diseases
SDG 3
Study investigates the underlying mechanisms of neurodegenerative diseases

Scientists from the University of Birmingham and the School of Medical Sciences at the Santa Casa de São Paulo are using cell reprogramming techniques to grasp at how Wolfram and Niemann-Pick syndromes act on the brain.


News about research projects funded by FAPESP and articulated with the SDGs: